Measuring the Interrelationships Between Cognitive Performance, Race/Ethnicity, Discrimination, Health Behaviors, and Physiological Dysregulation: A Path Analysis of the Multi-Ethnic Study of Atherosclerosis.

IF 2.2 3区医学 Q2 GERONTOLOGY

Journal of Aging and Health Pub Date : 2025-03-01 Epub Date: 2025-03-23 DOI:10.1177/08982643241309457

Sarah N Forrester, Joseph J Gallo, Jeannie-Marie Leoutsakos, Roland J Thorpe, Timothy M Hughes, Annette L Fitzpatrick, Stephen R Rapp, Teresa E Seeman

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引用次数: 0

Abstract

ObjectiveThe objective of this study was to examine the interrelationships between cognitive performance, race/ethnicity, discrimination, health behaviors, and physiological dysregulation.MethodsWe used data from the Multi-Ethnic Study of Atherosclerosis (MESA) (N = 1667). We used path analyses to examine the association between discrimination, physiological dysregulation, health behaviors, and cognitive performance using the Cognitive Ability Screening Instrument (CASI) at Exam 5 (2010-12) and Exam 6 (2016-18). We examined the relationship between discrimination at Exam 1 (2000-02) and physiological dysregulation at Exam 5. We used overall and ethnoracial-stratified path analysis. All models were adjusted for age, sex, site, depression, stress, socioeconomic status, and APOE-e4.ResultsPhysiological dysregulation was associated with worse cognitive performance in the full sample and among the White ethnoracial subgroup. Everyday discrimination was associated with better cognitive performance among Black participants.DiscussionAssociations between discrimination, physiological dysregulation, and cognitive performance vary and should be examined longitudinally.

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测量认知表现、种族/民族、歧视、健康行为和生理失调之间的相互关系：动脉粥样硬化多民族研究的路径分析

本研究的目的是探讨认知表现、种族/民族、歧视、健康行为和生理失调之间的相互关系。方法采用多民族动脉粥样硬化研究（MESA）的数据（N = 1667）。在考试5（2010-12）和考试6（2016-18）使用认知能力筛选工具（CASI），我们使用通径分析来检验歧视、生理失调、健康行为和认知表现之间的关系。我们研究了考试1（2000-02）的歧视和考试5的生理失调之间的关系。我们使用了整体和种族分层的通径分析。所有模型都根据年龄、性别、地点、抑郁、压力、社会经济地位和APOE-e4进行了调整。结果在全样本和白人亚组中，生理失调与较差的认知表现有关。黑人参与者的日常歧视与更好的认知表现有关。歧视、生理失调和认知表现之间的关系各不相同，应该进行纵向研究。

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来源期刊

Journal of Aging and Health Multiple-

CiteScore

5.60

自引率

3.60%

发文量

113

期刊介绍： The Journal of Aging and Health is an interdisciplinary forum for the presentation of research findings and scholarly exchange in the area of aging and health. Manuscripts are sought that deal with social and behavioral factors related to health and aging. Disciplines represented include the behavioral and social sciences, public health, epidemiology, demography, health services research, nursing, social work, medicine, and related disciplines. Although preference is given to manuscripts presenting the findings of original research, review and methodological pieces will also be considered.