{"title":"Intelligent Medical Assessment of the Impact of Anesthesia and Sedation Depth on Cognitive Function after Gynecological Laparoscopic Surgery.","authors":"Xuerong Zhang, Xueying Yang, Qiong Zhao","doi":"10.1016/j.slast.2025.100273","DOIUrl":null,"url":null,"abstract":"<p><p>In recent years, the research on post operational cognitive dysfunction (POCD) has received increasing attention. Some patients may experience complications such as mental disorder and memory impairment after gynecological laparoscopic surgery, which are cognitive, social, and personality issues of postoperative patients. This article divided patients after gynecological laparoscopic surgery into three groups based on different BIS (biological index) ranges. Before clinical use, artificial intelligence was used to sort out patients' complete history records, physical examination and analyze laboratory examination results, so as to determine the anesthetic dose and depth and reduce the incidence of accidents during surgery. This article adopted a combination of midazolam propofol radiocuronium bromide general anesthesia to adjust blood targeted concentration and maintain the depth of general anesthesia for patients. Using POCD as a starting point, the occurrence of POCD after gynecological laparoscopic surgery was evaluated through preoperative and postoperative neuropsychological measurements on the 14th day, as well as MMSE (Minimal State Examination) scores, and the impact of different anesthesia depths on POCD was also explored, which can provide a theoretical basis for the prevention and treatment of POCD. The MMSE score of Group A patients on the day before anesthesia was 23.9, while the MMSE score of Group B patients on the day before anesthesia was 23.8. The application of intelligent medicine in the study of the impact of anesthesia and sedation depth on gynecological laparoscopic surgery can improve the safety of surgery and the quality of life of patients, and has an important promoting role in clinical practice. The innovation of the research in this paper lies in the use of intelligent medical technology, through neuropsychological testing and MMSE scoring, in-depth analysis of the relationship between anesthesia depth and POCD.Combined anesthesia with midazolam and propofol was used, and the depth of anesthesia was precisely adjusted according to the BIS value.The study found that shallow anesthesia (low BIS value) may reduce the incidence of POCD, which provides theoretical and practical guidance for optimizing anesthesia strategies.</p>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":" ","pages":"100273"},"PeriodicalIF":2.5000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SLAS Technology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.slast.2025.100273","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, the research on post operational cognitive dysfunction (POCD) has received increasing attention. Some patients may experience complications such as mental disorder and memory impairment after gynecological laparoscopic surgery, which are cognitive, social, and personality issues of postoperative patients. This article divided patients after gynecological laparoscopic surgery into three groups based on different BIS (biological index) ranges. Before clinical use, artificial intelligence was used to sort out patients' complete history records, physical examination and analyze laboratory examination results, so as to determine the anesthetic dose and depth and reduce the incidence of accidents during surgery. This article adopted a combination of midazolam propofol radiocuronium bromide general anesthesia to adjust blood targeted concentration and maintain the depth of general anesthesia for patients. Using POCD as a starting point, the occurrence of POCD after gynecological laparoscopic surgery was evaluated through preoperative and postoperative neuropsychological measurements on the 14th day, as well as MMSE (Minimal State Examination) scores, and the impact of different anesthesia depths on POCD was also explored, which can provide a theoretical basis for the prevention and treatment of POCD. The MMSE score of Group A patients on the day before anesthesia was 23.9, while the MMSE score of Group B patients on the day before anesthesia was 23.8. The application of intelligent medicine in the study of the impact of anesthesia and sedation depth on gynecological laparoscopic surgery can improve the safety of surgery and the quality of life of patients, and has an important promoting role in clinical practice. The innovation of the research in this paper lies in the use of intelligent medical technology, through neuropsychological testing and MMSE scoring, in-depth analysis of the relationship between anesthesia depth and POCD.Combined anesthesia with midazolam and propofol was used, and the depth of anesthesia was precisely adjusted according to the BIS value.The study found that shallow anesthesia (low BIS value) may reduce the incidence of POCD, which provides theoretical and practical guidance for optimizing anesthesia strategies.
期刊介绍:
SLAS Technology emphasizes scientific and technical advances that enable and improve life sciences research and development; drug-delivery; diagnostics; biomedical and molecular imaging; and personalized and precision medicine. This includes high-throughput and other laboratory automation technologies; micro/nanotechnologies; analytical, separation and quantitative techniques; synthetic chemistry and biology; informatics (data analysis, statistics, bio, genomic and chemoinformatics); and more.