{"title":"A technical note on the posterior approach BDBO for treating Kümmell disease.","authors":"De-Xin Guo, Xiao-Wei Guo, Guang-Hui Yang, Yi-Bao Sun, Ya Song, Jin-Lu Wang, Wei-Bo Jiang, Tong Yu","doi":"10.1038/s41598-025-91923-y","DOIUrl":null,"url":null,"abstract":"<p><p>To evaluate the therapeutic efficacy of bone-disc-bone osteotomy (BDBO) via a posterior approach in combination with biomimetic bone grafting and pedicle screw implantation for the treatment of Kümmell disease complicated with kyphosis. Between March 2012 and June 2020, we retrospectively analyzed 22 patients who had Kümmell disease complicated with kyphosis and underwent BDBO in combination with biomimetic bone grafting and pedicle screw implantation. The kyphotic Cobb angle, visual analog scale (VAS), Oswestry Disability Index (ODI), and American Spinal Injury Association (ASIA) Impairment Scale were used to evaluate the effects of surgery. In addition, surgical conditions, including duration of surgery, intraoperative blood loss, and surgical complications, were recorded. The mean follow-up time was 32.86 months (range, 28.27 to 36.67). The mean operative time was 176.68 ± 25.96 min and the mean intraoperative blood loss was 281.24 ± 43.26 mL. The VAS, ODI, and kyphotic Cobb angles were significantly improved 1 week after surgery compared with preoperative assessments and remained well maintained at final follow-up. Eight patients (36.4%) had mild neurologic impairment before surgery, and their neurologic function normalized at final follow-up. The rate of intervertebral fusion at the final follow-up was 100%. One patient (4.5%) had an infected incision that healed after debridement. There was no case of instrumentation failure. BDBO in combination with biomimetic bone grafting and pedicle screw implantation is a novel, safe, effective and elective treatment strategy for patients who experienced Kümmell disease complicated by kyphosis.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"9892"},"PeriodicalIF":3.9000,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929767/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scientific Reports","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1038/s41598-025-91923-y","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
To evaluate the therapeutic efficacy of bone-disc-bone osteotomy (BDBO) via a posterior approach in combination with biomimetic bone grafting and pedicle screw implantation for the treatment of Kümmell disease complicated with kyphosis. Between March 2012 and June 2020, we retrospectively analyzed 22 patients who had Kümmell disease complicated with kyphosis and underwent BDBO in combination with biomimetic bone grafting and pedicle screw implantation. The kyphotic Cobb angle, visual analog scale (VAS), Oswestry Disability Index (ODI), and American Spinal Injury Association (ASIA) Impairment Scale were used to evaluate the effects of surgery. In addition, surgical conditions, including duration of surgery, intraoperative blood loss, and surgical complications, were recorded. The mean follow-up time was 32.86 months (range, 28.27 to 36.67). The mean operative time was 176.68 ± 25.96 min and the mean intraoperative blood loss was 281.24 ± 43.26 mL. The VAS, ODI, and kyphotic Cobb angles were significantly improved 1 week after surgery compared with preoperative assessments and remained well maintained at final follow-up. Eight patients (36.4%) had mild neurologic impairment before surgery, and their neurologic function normalized at final follow-up. The rate of intervertebral fusion at the final follow-up was 100%. One patient (4.5%) had an infected incision that healed after debridement. There was no case of instrumentation failure. BDBO in combination with biomimetic bone grafting and pedicle screw implantation is a novel, safe, effective and elective treatment strategy for patients who experienced Kümmell disease complicated by kyphosis.
期刊介绍:
We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections.
Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021).
•Engineering
Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live.
•Physical sciences
Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics.
•Earth and environmental sciences
Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems.
•Biological sciences
Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.
•Health sciences
The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.