Lipoblastoma of the Scalp in a Pediatric Patient.

IF 1.5 Q3 SURGERY
Plastic and Reconstructive Surgery Global Open Pub Date : 2025-03-21 eCollection Date: 2025-03-01 DOI:10.1097/GOX.0000000000006632
Constant P van Schalkwyk, Alzbeta Novotna, Kevin Ho
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Abstract

Lipoblastoma, a rare benign tumor composed of immature fat cells, typically arises in the first 3 years of life. Although commonly found in the extremities and trunk, occurrences on the scalp are exceedingly rare. We present a case report of a lipoblastoma located on the scalp of a 5-year-old female patient. The patient presented with a painless, gradually enlarging mass over a 6-month period. Clinical and radiological evaluation confirmed the presence of a well-defined, lobulated lesion with adipose density. Surgical excision was performed, and histopathologic examination revealed characteristic features of lipoblastoma, including lipoblast-like cells and lobules of adipose tissue, separated by fibrous connective tissue septae of varying thickness surrounded by a fibrocartilaginous capsule. To our knowledge, this is the fourth documented case of lipoblastoma originating in the scalp region in a pediatric patient. Given the rarity of lipoblastoma in this location, this case highlights the importance of considering lipoblastoma as a differential diagnosis when evaluating scalp masses in children. Awareness of atypical presentations and histopathologic features can aid in accurate diagnosis and appropriate management, which usually involves complete surgical resection. Further studies are warranted to explore the genetic and molecular underpinnings of these unique cases, contributing to a better understanding of the pathogenesis of lipoblastomas in various anatomical sites.

儿科患者头皮脂肪母细胞瘤。
脂肪母细胞瘤是一种罕见的由未成熟脂肪细胞组成的良性肿瘤,通常发生在生命的前3年。虽然常见于四肢和躯干,但发生在头皮上是非常罕见的。我们提出一个病例报告的脂肪母细胞瘤位于头皮上的一个5岁的女性患者。患者表现为无痛,肿块逐渐增大6个月。临床和放射学评估证实存在一个明确的,分叶状病变与脂肪密度。手术切除,组织病理学检查显示成脂细胞瘤的特征,包括成脂细胞样细胞和脂肪组织小叶,由纤维软骨包膜包围的不同厚度的纤维结缔组织隔膜隔开。据我们所知,这是第四个记录的病例脂肪母细胞瘤起源于头皮区域的儿科患者。鉴于脂肪母细胞瘤在该部位的罕见性,本病例强调了在评估儿童头皮肿块时将脂肪母细胞瘤作为鉴别诊断的重要性。意识到不典型的表现和组织病理学特征有助于准确的诊断和适当的处理,这通常需要完全的手术切除。进一步的研究需要探索这些独特病例的遗传和分子基础,有助于更好地了解脂肪母细胞瘤在不同解剖部位的发病机制。
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来源期刊
CiteScore
2.20
自引率
13.30%
发文量
1584
审稿时长
10 weeks
期刊介绍: Plastic and Reconstructive Surgery—Global Open is an open access, peer reviewed, international journal focusing on global plastic and reconstructive surgery.Plastic and Reconstructive Surgery—Global Open publishes on all areas of plastic and reconstructive surgery, including basic science/experimental studies pertinent to the field and also clinical articles on such topics as: breast reconstruction, head and neck surgery, pediatric and craniofacial surgery, hand and microsurgery, wound healing, and cosmetic and aesthetic surgery. Clinical studies, experimental articles, ideas and innovations, and techniques and case reports are all welcome article types. Manuscript submission is open to all surgeons, researchers, and other health care providers world-wide who wish to communicate their research results on topics related to plastic and reconstructive surgery. Furthermore, Plastic and Reconstructive Surgery—Global Open, a complimentary journal to Plastic and Reconstructive Surgery, provides an open access venue for the publication of those research studies sponsored by private and public funding agencies that require open access publication of study results. Its mission is to disseminate high quality, peer reviewed research in plastic and reconstructive surgery to the widest possible global audience, through an open access platform. As an open access journal, Plastic and Reconstructive Surgery—Global Open offers its content for free to any viewer. Authors of articles retain their copyright to the materials published. Additionally, Plastic and Reconstructive Surgery—Global Open provides rapid review and publication of accepted papers.
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