{"title":"Intraparotid Facial Nerve Schwannoma: A Comprehensive Review of 70 Cases at One Single Institution.","authors":"Lingli Huang, Wei Xu, Wenya Zhu, Hao Lu, Shengwen Liu, Wenjun Yang, Wanlin Xu","doi":"10.1111/odi.15323","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The current study aimed to analyze the clinical characteristics, diagnosis, and surgical outcomes of intraparotid facial nerve schwannoma (IPFNS) and propose a more definitive therapeutic algorithm for IPFNS.</p><p><strong>Methods: </strong>Between January 2018 and December 2023, all the cases of IPFNS at our single institution were retrospectively reviewed.</p><p><strong>Results: </strong>In total, 70 patients were included in this study. Among them, 23 (32.3%) were men and 47 (67.7%) were women. The patients commonly presented with a painless parotid mass, and three patients complained of facial paralysis. Magnetic resonance imaging (MRI) had the highest diagnostic efficacy (37.1%) among all the evaluation techniques used. Marchioni's classification and surgical method were significantly associated with postoperative facial function. In terms of surgical interventions, stripping surgery was suitable for type A tumors, while for types B, C, and D tumors, intracapsular enucleation with a microscope was recommended to decrease the influence of the procedure on facial nerve function.</p><p><strong>Conclusions: </strong>IPFNS is a rare disease, whose diagnosis and management remain challenging. MRI is the preferred preoperative diagnostic method. Preoperative facial nerve function, tumor location, and patients' preferences are key factors in the decision-making process of IPFNS treatment.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/odi.15323","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The current study aimed to analyze the clinical characteristics, diagnosis, and surgical outcomes of intraparotid facial nerve schwannoma (IPFNS) and propose a more definitive therapeutic algorithm for IPFNS.
Methods: Between January 2018 and December 2023, all the cases of IPFNS at our single institution were retrospectively reviewed.
Results: In total, 70 patients were included in this study. Among them, 23 (32.3%) were men and 47 (67.7%) were women. The patients commonly presented with a painless parotid mass, and three patients complained of facial paralysis. Magnetic resonance imaging (MRI) had the highest diagnostic efficacy (37.1%) among all the evaluation techniques used. Marchioni's classification and surgical method were significantly associated with postoperative facial function. In terms of surgical interventions, stripping surgery was suitable for type A tumors, while for types B, C, and D tumors, intracapsular enucleation with a microscope was recommended to decrease the influence of the procedure on facial nerve function.
Conclusions: IPFNS is a rare disease, whose diagnosis and management remain challenging. MRI is the preferred preoperative diagnostic method. Preoperative facial nerve function, tumor location, and patients' preferences are key factors in the decision-making process of IPFNS treatment.
期刊介绍:
Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.