The Conservative Treatment of a Rare Postoperative Complication of DBS-Brain Abscess: Case Series.

IF 2.9 3区医学 Q2 INFECTIOUS DISEASES

Infection and Drug Resistance Pub Date : 2025-03-17 eCollection Date: 2025-01-01 DOI:10.2147/IDR.S497124

Guanghan Lu, Jingxuan Liu, Xiang Wei, Jiuqi Yan, Jian Sun, Wenwen Dong, Liang Zhao, Chang Qiu, Bei Luo, Wenbin Zhang

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Abstract

Background: Deep Brain Stimulation (DBS) is an established treatment option for movement disorders such as Parkinson's disease and dystonia, so more and more patients (over 160,000 patients till 2019) worldwide have undergone DBS for a variety of neurological and non-neurological conditions, with numbers increasing each year. This case series primarily discusses a very rare complication following DBS surgery -- brain abscess.

Case presentation: We administered vancomycin and metronidazole to patients who developed brain abscesses after undergoing DBS surgery based on previous literature. After treatment, the abscess lesions and infection symptoms completely resolved, resulting in a good therapeutic outcome without the removal of the DBS system.

Conclusion: In previous studies, similar cases always involved surgical intervention to drain the pus while also removing the DBS system; however, in our cases, the patient did not have the DBS system removed and achieved a good prognosis. To our knowledge, our two cases are among the few where a conservative treatment approach has been used for brain abscesses after DBS surgery.

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来源期刊

Infection and Drug Resistance Medicine-Pharmacology (medical)

CiteScore

5.60

自引率

7.70%

发文量

826

审稿时长

16 weeks

期刊介绍： About Journal Editors Peer Reviewers Articles Article Publishing Charges Aims and Scope Call For Papers ISSN: 1178-6973 Editor-in-Chief: Professor Suresh Antony An international, peer-reviewed, open access journal that focuses on the optimal treatment of infection (bacterial, fungal and viral) and the development and institution of preventative strategies to minimize the development and spread of resistance.