Validity of the Pancreatic Cancer Registry in Southern Denmark.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Danish medical journal Pub Date : 2025-02-14 DOI:10.61409/A08240545

Cara Manmeet Bhuller, Michael Bau Mortensen, Henriette Engberg, Claus Wilki Fristrup

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引用次数: 0

Abstract

Introduction: The Danish Pancreatic Cancer Database (DPCD) uses data from the Danish National Patient Registry (DNPR) and includes patients with pancreatic carcinomas, duodenal and ampullary cancers. Due to the aggressive nature of pancreatic cancer, some patients never receive diagnostic work-up at a hepato-pancreatico-biliary centre. The aim of this study was to explore the validity of the registration of the pancreatic cancer diagnosis for patients living in the Region of Southern Denmark reported in the DNPR but not included in the DPCD.

Methods: This study is a descriptive analysis of a historical cohort of patients registered with a diagnosis of pancreatic cancer (DC 25.0-25.9, DC 24.1, DC 17.0, excluding DC 25.4) from 1 July 2019 to 30 June 2022, in the DNPR but with no registration in the DPCD.

Results: We identified 155 patients with a relevant diagnosis in the DNPR who were not included in the DPCD. A total of 62 patients (40%) represented potentially valid cases of pancreatic cancer, whereas 73 patients (47%) had pNET and 20 patients (13%) had an entirely different diagnosis. Only seven patients (11%) of the potentially valid pancreatic cancer group and 4.5% of the total study cohort had a histology-verified diagnosis of pancreatic cancer. The DNPR contained (93/944) 10% with an incorrect diagnosis of pancreatic cancer and 6% with an uncertain diagnosis.

Conclusions: This study demonstrates a high level of completeness for the DPCD in the Region of Southern Denmark. Invalid registration of the pancreatic cancer diagnosis is an important limitation in using the DNPR, which is the only data source for identifying patients with pancreatic cancer in Denmark.

Funding: None.

Trial registration: Not relevant.

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丹麦南部胰腺癌登记的有效性。

简介：丹麦胰腺癌数据库（DPCD）使用来自丹麦国家患者登记处（DNPR）的数据，包括胰腺癌、十二指肠癌和壶腹癌患者。由于胰腺癌的侵袭性，一些患者从未在肝胰胆中心接受诊断检查。本研究的目的是探讨居住在丹麦南部地区的患者胰腺癌诊断登记的有效性，这些患者在DNPR中报告，但未包括在DPCD中。方法：本研究是对2019年7月1日至2022年6月30日登记为胰腺癌诊断的患者（DC 25.0-25.9, DC 24.1, DC 17.0，不包括DC 25.4）的历史队列进行描述性分析，这些患者在DNPR中登记，但在DPCD中没有登记。结果：我们确定了155例在dppr中有相关诊断但未包括在DPCD中的患者。共有62例患者（40%）代表潜在的胰腺癌病例，而73例患者（47%）有pNET， 20例患者（13%）有完全不同的诊断。在潜在有效的胰腺癌组中，只有7名患者（11%）和总研究队列的4.5%有组织学证实的胰腺癌诊断。DNPR中有（93/944）10%诊断不正确，6%诊断不确定。结论：本研究证明了丹麦南部地区DPCD的高水平完整性。胰腺癌诊断的无效登记是使用DNPR的一个重要限制，DNPR是丹麦识别胰腺癌患者的唯一数据来源。资金:没有。试验注册：不相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Danish medical journal MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

6.20%

发文量

审稿时长

3-8 weeks

期刊介绍： The Danish Medical Journal (DMJ) is a general medical journal. The journal publish original research in English – conducted in or in relation to the Danish health-care system. When writing for the Danish Medical Journal please remember target audience which is the general reader. This means that the research area should be relevant to many readers and the paper should be presented in a way that most readers will understand the content. DMJ will publish the following articles: • Original articles • Protocol articles from large randomized clinical trials • Systematic reviews and meta-analyses • PhD theses from Danish faculties of health sciences • DMSc theses from Danish faculties of health sciences.