Respiratory morbidity in newborns with a gestational age at or above 32 weeks.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Danish medical journal Pub Date : 2025-01-27 DOI:10.61409/A03240200

Michelle Pihl Larsen, Anna Elisabeth Lewis, Anne Mette Plomgaard, Bo Mølholm Hansen

{"title":"Respiratory morbidity in newborns with a gestational age at or above 32 weeks.","authors":"Michelle Pihl Larsen, Anna Elisabeth Lewis, Anne Mette Plomgaard, Bo Mølholm Hansen","doi":"10.61409/A03240200","DOIUrl":null,"url":null,"abstract":"Introduction: This study aimed to investigate the reasons for early admissions to two neonatal intensive care units (NICU) for respiratory morbidity, defined as any disease presenting with respiratory symptoms in moderate to late preterm and term infants.Methods: This retrospective cohort study included all infants with gestational age (GA) ≥ 32 weeks admitted to the NICUs in 2021 in two hospitals covering almost 20% of all births in Denmark.Results: In total, 921 infants (8% of all liveborn with a GA ≥ 32 weeks) were admitted to the NICUs within the first 24 hours of life. Among these, 60% were diagnosed with respiratory morbidity, with a corresponding incidence of 35% and 3.2% in preterm and term infants, respectively. In the term group, the median duration of respiratory support was five hours, with 73% being treated for less than 12 hours. In the preterm group, respiratory support was also brief (19 hours median), and 30 (15%) infants developed respiratory distress syndrome (RDS) (5.3% incidence of liveborn with a GA of 32-36 weeks).Conclusions: In term newborns, mild respiratory morbidity is the most frequent cause for early admission, and the duration of treatment is often short. In moderate to late preterm infants, respiratory morbidity also tends to be mild, though 15% of the admitted infants developed RDS.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"72 2","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Danish medical journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.61409/A03240200","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: This study aimed to investigate the reasons for early admissions to two neonatal intensive care units (NICU) for respiratory morbidity, defined as any disease presenting with respiratory symptoms in moderate to late preterm and term infants.

Methods: This retrospective cohort study included all infants with gestational age (GA) ≥ 32 weeks admitted to the NICUs in 2021 in two hospitals covering almost 20% of all births in Denmark.

Results: In total, 921 infants (8% of all liveborn with a GA ≥ 32 weeks) were admitted to the NICUs within the first 24 hours of life. Among these, 60% were diagnosed with respiratory morbidity, with a corresponding incidence of 35% and 3.2% in preterm and term infants, respectively. In the term group, the median duration of respiratory support was five hours, with 73% being treated for less than 12 hours. In the preterm group, respiratory support was also brief (19 hours median), and 30 (15%) infants developed respiratory distress syndrome (RDS) (5.3% incidence of liveborn with a GA of 32-36 weeks).

Conclusions: In term newborns, mild respiratory morbidity is the most frequent cause for early admission, and the duration of treatment is often short. In moderate to late preterm infants, respiratory morbidity also tends to be mild, though 15% of the admitted infants developed RDS.

Funding: None.

Trial registration: Not relevant.

查看原文本刊更多论文

胎龄在32周或以上的新生儿的呼吸道疾病。

前言：本研究旨在调查两家新生儿重症监护病房（NICU）因呼吸系统疾病早期入院的原因，呼吸系统疾病的定义是中度至晚期早产儿和足月婴儿出现呼吸系统症状的任何疾病。方法：本回顾性队列研究纳入了2021年丹麦两家医院nicu收治的所有胎龄≥32周的婴儿，覆盖了丹麦所有新生儿的近20%。结果：共有921名婴儿（占所有GA≥32周的活产婴儿的8%）在出生后24小时内入住新生儿重症监护病房。其中，60%被诊断为呼吸道疾病，相应的早产儿和足月儿发病率分别为35%和3.2%。在长期组中，呼吸支持的中位持续时间为5小时，73%的患者治疗时间少于12小时。在早产儿组，呼吸支持也很短暂（中位19小时），30名（15%）婴儿出现呼吸窘迫综合征（RDS）（32-36周的活产发生率为5.3%）。结论：在足月新生儿中，轻度呼吸道疾病是早期入院的最常见原因，且治疗时间往往较短。在中度至晚期早产儿中，呼吸道疾病的发病率也往往是轻微的，尽管入院的婴儿中有15%发生了RDS。资金:没有。试验注册：不相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Danish medical journal MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

6.20%

发文量

审稿时长

3-8 weeks

期刊介绍： The Danish Medical Journal (DMJ) is a general medical journal. The journal publish original research in English – conducted in or in relation to the Danish health-care system. When writing for the Danish Medical Journal please remember target audience which is the general reader. This means that the research area should be relevant to many readers and the paper should be presented in a way that most readers will understand the content. DMJ will publish the following articles: • Original articles • Protocol articles from large randomized clinical trials • Systematic reviews and meta-analyses • PhD theses from Danish faculties of health sciences • DMSc theses from Danish faculties of health sciences.