Immediate prepectoral breast reconstruction using bovine pericardium matrix.

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Thomas Takahashi Bentzon, Maja Abu-Khalil, Alessandro Venzo, Dina Reem Matzen, Tina Engberg Damsgaard
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引用次数: 0

Abstract

Introduction: Immediate, implant-based breast reconstruction has become increasingly popular as a single-stage procedure with prepectoral placement of the implant following the introduction of biologic matrices. Only a few studies have described the use of bovine pericardium matrixTutomesh, a xenograft derived from bovine pericardium - and the use of laser-assisted indocyanine green angiography (ICG-A) to assess skin flap perfusion.

Methods: All patients who underwent a mastectomy followed by immediate reconstruction using prepectoral direct-to-implant with bovine pericardium from July 2019 to June 2021 were included. Complications were registered using the Clavien-Dindo classification. Postsurgical complications were analysed with multivariate logistic regression and feature selection.

Results: A total of 81 prepectoral breast reconstructions were performed in 56 patients. The overall complication rate was 38.2%, and 14.3% required reoperation. Implant loss occurred in 3.7%. Multivariate logistic regression analysis demonstrated a statistically significant association between the risk of skin necrosis and previous breast surgery (p = 0.020) along with an increasing risk of implant rotation with increasing age (p = 0.010). The median follow-up was 9.9 months, and 11.1% of the breast reconstructions required postsurgical aesthetic correction.

Conclusions: Bovine pericardium may be used in prepectoral breast reconstruction with a good outcome. Careful patient selection is crucial, and ICG-A is helpful in reducing the risk of post-surgical complications.

Funding: None.

Trial registration: Not relevant.

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来源期刊
Danish medical journal
Danish medical journal MEDICINE, GENERAL & INTERNAL-
CiteScore
2.30
自引率
6.20%
发文量
78
审稿时长
3-8 weeks
期刊介绍: The Danish Medical Journal (DMJ) is a general medical journal. The journal publish original research in English – conducted in or in relation to the Danish health-care system. When writing for the Danish Medical Journal please remember target audience which is the general reader. This means that the research area should be relevant to many readers and the paper should be presented in a way that most readers will understand the content. DMJ will publish the following articles: • Original articles • Protocol articles from large randomized clinical trials • Systematic reviews and meta-analyses • PhD theses from Danish faculties of health sciences • DMSc theses from Danish faculties of health sciences.
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