Immediate prepectoral breast reconstruction using bovine pericardium matrix.

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Thomas Takahashi Bentzon, Maja Abu-Khalil, Alessandro Venzo, Dina Reem Matzen, Tina Engberg Damsgaard
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引用次数: 0

Abstract

Introduction: Immediate, implant-based breast reconstruction has become increasingly popular as a single-stage procedure with prepectoral placement of the implant following the introduction of biologic matrices. Only a few studies have described the use of bovine pericardium matrixTutomesh, a xenograft derived from bovine pericardium - and the use of laser-assisted indocyanine green angiography (ICG-A) to assess skin flap perfusion.

Methods: All patients who underwent a mastectomy followed by immediate reconstruction using prepectoral direct-to-implant with bovine pericardium from July 2019 to June 2021 were included. Complications were registered using the Clavien-Dindo classification. Postsurgical complications were analysed with multivariate logistic regression and feature selection.

Results: A total of 81 prepectoral breast reconstructions were performed in 56 patients. The overall complication rate was 38.2%, and 14.3% required reoperation. Implant loss occurred in 3.7%. Multivariate logistic regression analysis demonstrated a statistically significant association between the risk of skin necrosis and previous breast surgery (p = 0.020) along with an increasing risk of implant rotation with increasing age (p = 0.010). The median follow-up was 9.9 months, and 11.1% of the breast reconstructions required postsurgical aesthetic correction.

Conclusions: Bovine pericardium may be used in prepectoral breast reconstruction with a good outcome. Careful patient selection is crucial, and ICG-A is helpful in reducing the risk of post-surgical complications.

Funding: None.

Trial registration: Not relevant.

牛心包基质即刻乳前乳房重建。
简介:立即,基于植入物的乳房重建已经越来越流行,作为一种单阶段手术,在引入生物基质后,植入物在乳房前放置。只有少数研究描述了使用牛心包基质(一种源自牛心包的异种移植物)和使用激光辅助吲哚菁绿血管造影(ICG-A)来评估皮瓣灌注。方法:纳入2019年7月至2021年6月期间所有接受乳房切除术后立即使用牛心包直接植入前乳房重建的患者。使用Clavien-Dindo分类记录并发症。采用多因素logistic回归和特征选择对术后并发症进行分析。结果:56例患者共行81例乳房重建。总并发症发生率为38.2%,14.3%需要再次手术。种植体损失发生率为3.7%。多因素logistic回归分析显示,皮肤坏死风险与既往乳房手术(p = 0.020)以及植入物旋转风险随年龄增长而增加(p = 0.010)之间存在统计学显著相关。中位随访时间为9.9个月,11.1%的乳房重建术后需要进行美学矫正。结论:牛心包膜可用于产前乳房再造术,效果良好。仔细的患者选择是至关重要的,ICG-A有助于减少术后并发症的风险。资金:没有。试验注册:不相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Danish medical journal
Danish medical journal MEDICINE, GENERAL & INTERNAL-
CiteScore
2.30
自引率
6.20%
发文量
78
审稿时长
3-8 weeks
期刊介绍: The Danish Medical Journal (DMJ) is a general medical journal. The journal publish original research in English – conducted in or in relation to the Danish health-care system. When writing for the Danish Medical Journal please remember target audience which is the general reader. This means that the research area should be relevant to many readers and the paper should be presented in a way that most readers will understand the content. DMJ will publish the following articles: • Original articles • Protocol articles from large randomized clinical trials • Systematic reviews and meta-analyses • PhD theses from Danish faculties of health sciences • DMSc theses from Danish faculties of health sciences.
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