Hydrogel-based 3D printing technology: From interfacial engineering to precision medicine

IF 15.9 1区化学 Q1 CHEMISTRY, PHYSICAL

Advances in Colloid and Interface Science Pub Date : 2025-03-19 DOI:10.1016/j.cis.2025.103481

Haojie Wu , Jibo Diao , Xinrong Li , Dongmei Yue , Gaohong He , Xiaobin Jiang , Peipei Li

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Abstract

Advances in 3D printing technology and the development of hydrogel-based inks have significantly enhanced the potential of precision medicine, promoting progress in medical diagnosis and treatment. The development of 3D printing enables the fabrication of complex gradient structures that emulate natural tissue environments, while advancements in interface engineering facilitate the precise control of interface properties, thereby enhancing the performance of hydrogels in biomedical applications. This review focuses on the latest advancements in three critical 3D printing application areas: efficient real-time detection, drug delivery systems, and regenerative medicine. The application of 3D printing technology enhances nucleic acid-based molecular diagnostic platforms and wearable biosensors for real-time monitoring of physiological parameters, thereby providing robust support for early disease diagnosis. Additionally, it facilitates the development of targeted and controlled drug delivery systems, which offer promising methods for efficient drug utilization, and enables the construction of complex tissue and organ structures with bioactivity and functionality, providing new solutions for regenerative medicine. Collectively, these advancements propel the ongoing progress and development of precision medicine. Furthermore, the challenges associated with 3D printing technology in these three major applications are discussed along with an outlook on prospects.

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来源期刊

Advances in Colloid and Interface Science 化学-物理化学

CiteScore

28.50

自引率

2.60%

发文量

175

审稿时长

31 days

期刊介绍： "Advances in Colloid and Interface Science" is an international journal that focuses on experimental and theoretical developments in interfacial and colloidal phenomena. The journal covers a wide range of disciplines including biology, chemistry, physics, and technology. The journal accepts review articles on any topic within the scope of colloid and interface science. These articles should provide an in-depth analysis of the subject matter, offering a critical review of the current state of the field. The author's informed opinion on the topic should also be included. The manuscript should compare and contrast ideas found in the reviewed literature and address the limitations of these ideas. Typically, the articles published in this journal are written by recognized experts in the field.