3-Fluorooxindoles from indolin-2-ones by Selectfluor

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2025-02-26 DOI:10.1016/j.tet.2025.134556

Hui Qin , Guo-Liang Wei , Fu-Wei Wang , Xiao-Hong Mao , Mei-Hua Bao , Yi-Wen Zhang , Ping Huang , Xiao-Wei Zheng

引用次数: 0

Abstract

Herein, a practical and efficient method for fluorinating various indolin-2-ones under mild conditions was presented, utilizing selectfluor as a cost-effective fluorination reagent. Notably, the protocol operated under environmentally friendly conditions, facilitating the generation of various substituted indolin-2-ones into corresponding fluorinated indolin-2-ones in moderate to good yields, all without the need for an alkali source or heating.

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.