Sodium channel blockers for the treatment of focal epilepsy: A Chinese expert consensus

IF 2.7 3区医学 Q2 CLINICAL NEUROLOGY

Seizure-European Journal of Epilepsy Pub Date : 2025-03-12 DOI:10.1016/j.seizure.2025.02.016

Raowei Yan , Hesheng Zhang , Zhen Hong , Weiping Liao , Xuefeng Wang , Yuping Wang , Bo Xiao , Yanchun Deng , Meiping Ding , Xiong Han , Shuli Liang , Weihong Lin , Xiaorong Liu , Xuewu Liu , Xin Wang , Tiancheng Wang , Xiangqing Wang , Xiaoshan Wang , Peimin Yu , Kai Zhang , Dong Zhou

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引用次数: 0

Abstract

Purpose

To provide consensus-based recommendations for the use of sodium channel blockers (SCBs) in the management of focal epilepsy.

Methods

A three-round modified Delphi procedure was conducted among a Delphi panel of 24 Chinese experts to build a consensus. A steering committee developed 9 statements related to SCBs for the treatment of focal epilepsy, and these statements were evaluated and voted upon by the expert panel.

Results

The expert panel achieved consensus on nine statements regarding the treatment recommendations for oxcarbazepine, lamotrigine, lacosamide, eslicarbazepine, topiramate, zonisamide and cenobamate in focal epilepsy patients and treatment adjustments for SCBs.

Conclusion

This is a Chinese expert consensus on the use of SCBs in focal epilepsy developed using the modified Delphi method. These recommendations can help clinicians in their practice and guide future research.

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来源期刊

Seizure-European Journal of Epilepsy 医学-临床神经学

CiteScore

5.60

自引率

6.70%

发文量

231

审稿时长

34 days

期刊介绍： Seizure - European Journal of Epilepsy is an international journal owned by Epilepsy Action (the largest member led epilepsy organisation in the UK). It provides a forum for papers on all topics related to epilepsy and seizure disorders.