Tissue Engineering and Spinal Cord Injury Repair

IF 10.1 1区工程技术 Q1 ENGINEERING, MULTIDISCIPLINARY

Engineering Pub Date : 2025-03-01 DOI:10.1016/j.eng.2024.12.027

Lai Xu , Songlin Zhou , Xiu Dai , Xiaosong Gu , Zhaolian Ouyang

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引用次数: 0

Abstract

Tissue engineering and regenerative medicine is a new interdisciplinary subject integrating life science, material science, engineering technology, and clinical medicine. Over the last ten years, significant advancements have been achieved in the study of biomaterials and tissue engineering. Progress in the field of tissue engineering and regenerative medicine can result in optimal tissue regeneration and effective functional reconstruction. Spinal cord injury (SCI) is the most severe complication of spinal trauma and frequently results in significant functional impairments in the lower extremities of the affected segment. Repair of SCI is a medical challenge worldwide. Advancements in tissue engineering theory and technology offer fresh opportunities for addressing SCI, as well as providing new strategies and methodologies to tackle the challenges associated with repairing and reconstructing spinal cord function. This article provides an overview of the latest developments in tissue engineering and SCI repair, focusing on biomaterials, cells, and active factors. It also introduces nine key components related to SCI and proposes innovative approaches for repairing and functionally reconstructing the injured spinal cord.

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来源期刊

Engineering Environmental Science-Environmental Engineering

自引率

1.60%

发文量

335

审稿时长

35 days

期刊介绍： Engineering, an international open-access journal initiated by the Chinese Academy of Engineering (CAE) in 2015, serves as a distinguished platform for disseminating cutting-edge advancements in engineering R&D, sharing major research outputs, and highlighting key achievements worldwide. The journal's objectives encompass reporting progress in engineering science, fostering discussions on hot topics, addressing areas of interest, challenges, and prospects in engineering development, while considering human and environmental well-being and ethics in engineering. It aims to inspire breakthroughs and innovations with profound economic and social significance, propelling them to advanced international standards and transforming them into a new productive force. Ultimately, this endeavor seeks to bring about positive changes globally, benefit humanity, and shape a new future.