A rare case of intrascrotal lipoblastoma in a 2-year-old: Case report and literature review

Abstract

Lipoblastomas are rare benign tumors arising from embryonal fat tissues, commonly occurring in early childhood. Scrotal presentation is exceedingly rare, with 18 cases reported in the literature. We present a 2-year-old male with a 5-month history of painless scrotal swelling, initially suspected of being malignant. Imaging suggested the possibility of atypical lipoma. The patient underwent orchiectomy. Histopathologic examination confirmed the diagnosis of lipoblastoma, with no MDM2 amplification. After two years of follow-up, the patient remains recurrence-free. This case highlights the challenges of diagnosing pediatric scrotal masses preoperatively and highlights the importance of a multidisciplinary approach for accurate diagnosis and management.