{"title":"Chemical constituents from the Algerian ash Fraxinus dimorpha Coss. & Dur. and their chemotaxonomic significance","authors":"Sabrine Bouhentala , Sonia Chabani , Mohammed Benkhaled , Hamada Haba","doi":"10.1016/j.bse.2025.105007","DOIUrl":null,"url":null,"abstract":"<div><div>The investigation of the chemical composition of <em>n</em>-hexane and ethyl acetate extracts from the aerial parts of <em>Fraxinus dimorpha</em> resulted in the isolation of a new compound (<strong>1</strong>), identified as a fatty acid ester, along with fifteen previously reported secondary metabolites (<strong>2</strong>–<strong>16</strong>). These included one fatty acid (<strong>2</strong>), four triterpenoids (<strong>3</strong>–<strong>6</strong>), two phytosterols (<strong>7</strong> and <strong>8</strong>), three coumarins (<strong>9</strong>–<strong>11</strong>), one phenylpropanoid glucoside (<strong>12</strong>), three secoiridoids (<strong>13</strong>–<strong>15</strong>), and one free sugar (<strong>16</strong>). Among them, undecanoic acid (<strong>2</strong>), oleanolic acid acetate (<strong>4</strong>), lupeol (<strong>5</strong>) and lupenone (<strong>6</strong>) were identified for the first time within the <em>Fraxinus</em> genus. The structures of isolated compounds (<strong>1</strong>–<strong>16</strong>) were elucidated through extensive spectroscopic analyses such as 1D and 2D-NMR and HR-ESI-MS as well as by comparing experimental data with those reported in the literature. Additionally, the chemotaxonomic significance of the isolated bioactive compounds was discussed.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"121 ","pages":"Article 105007"},"PeriodicalIF":1.4000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemical Systematics and Ecology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0305197825000560","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The investigation of the chemical composition of n-hexane and ethyl acetate extracts from the aerial parts of Fraxinus dimorpha resulted in the isolation of a new compound (1), identified as a fatty acid ester, along with fifteen previously reported secondary metabolites (2–16). These included one fatty acid (2), four triterpenoids (3–6), two phytosterols (7 and 8), three coumarins (9–11), one phenylpropanoid glucoside (12), three secoiridoids (13–15), and one free sugar (16). Among them, undecanoic acid (2), oleanolic acid acetate (4), lupeol (5) and lupenone (6) were identified for the first time within the Fraxinus genus. The structures of isolated compounds (1–16) were elucidated through extensive spectroscopic analyses such as 1D and 2D-NMR and HR-ESI-MS as well as by comparing experimental data with those reported in the literature. Additionally, the chemotaxonomic significance of the isolated bioactive compounds was discussed.
期刊介绍:
Biochemical Systematics and Ecology is devoted to the publication of original papers and reviews, both submitted and invited, in two subject areas: I) the application of biochemistry to problems relating to systematic biology of organisms (biochemical systematics); II) the role of biochemistry in interactions between organisms or between an organism and its environment (biochemical ecology).
In the Biochemical Systematics subject area, comparative studies of the distribution of (secondary) metabolites within a wider taxon (e.g. genus or family) are welcome. Comparative studies, encompassing multiple accessions of each of the taxa within their distribution are particularly encouraged. Welcome are also studies combining classical chemosystematic studies (such as comparative HPLC-MS or GC-MS investigations) with (macro-) molecular phylogenetic studies. Studies that involve the comparative use of compounds to help differentiate among species such as adulterants or substitutes that illustrate the applied use of chemosystematics are welcome. In contrast, studies solely employing macromolecular phylogenetic techniques (gene sequences, RAPD studies etc.) will be considered out of scope. Discouraged are manuscripts that report known or new compounds from a single source taxon without addressing a systematic hypothesis. Also considered out of scope are studies using outdated and hard to reproduce macromolecular techniques such as RAPDs in combination with standard chemosystematic techniques such as GC-FID and GC-MS.