Application and recent progress of MXene-based bioactive materials in wound management

Jiahao Guo , Xiaodong Zhu , Beibei Liang , Xuelian Gu , Cong Wu , Ang Li , Wei Li
{"title":"Application and recent progress of MXene-based bioactive materials in wound management","authors":"Jiahao Guo ,&nbsp;Xiaodong Zhu ,&nbsp;Beibei Liang ,&nbsp;Xuelian Gu ,&nbsp;Cong Wu ,&nbsp;Ang Li ,&nbsp;Wei Li","doi":"10.1016/j.ntm.2025.100079","DOIUrl":null,"url":null,"abstract":"<div><div>Wound management is one of the major challenges in the biomedical field, where wound ulceration and bacterial infections cause systemic inflammatory reactions or scarring in patients, seriously affecting the quality of life and causing great economic pressure. Smart bioactive materials offer new therapeutic strategies for wound management and monitoring, providing a tailored option for wound repair. MXene, as a 2D functional and tunable material, exhibits unique advantages and enormous potential in promoting cell growth, angiogenesis, recruiting immune cells, avoiding infections, and biological signal transmission. This review details the benefits of MXene-based materials in the field of tissue repair and addresses the key challenges faced by different wounds, reflecting excellent bioactivity and organismal suitability. Notably, MXene can function as a smart surrogate device, enabling precise assessments for wound monitoring and care. This development signifies a paradigm shift towards a novel era of non-invasive monitoring of the healing cycle. Nevertheless, strategies for regenerative tissue engineering employing MXene-based materials encounter certain challenges and difficulties, which include ensuring long-term bioactive function, developing novel material types, and meeting individual clinical needs. Finally, the future research directions and technological developments of MXene-based materials in wound management were briefly discussed.</div></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"4 ","pages":"Article 100079"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nano TransMed","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S279067602500010X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Wound management is one of the major challenges in the biomedical field, where wound ulceration and bacterial infections cause systemic inflammatory reactions or scarring in patients, seriously affecting the quality of life and causing great economic pressure. Smart bioactive materials offer new therapeutic strategies for wound management and monitoring, providing a tailored option for wound repair. MXene, as a 2D functional and tunable material, exhibits unique advantages and enormous potential in promoting cell growth, angiogenesis, recruiting immune cells, avoiding infections, and biological signal transmission. This review details the benefits of MXene-based materials in the field of tissue repair and addresses the key challenges faced by different wounds, reflecting excellent bioactivity and organismal suitability. Notably, MXene can function as a smart surrogate device, enabling precise assessments for wound monitoring and care. This development signifies a paradigm shift towards a novel era of non-invasive monitoring of the healing cycle. Nevertheless, strategies for regenerative tissue engineering employing MXene-based materials encounter certain challenges and difficulties, which include ensuring long-term bioactive function, developing novel material types, and meeting individual clinical needs. Finally, the future research directions and technological developments of MXene-based materials in wound management were briefly discussed.
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信