Reading Performances in Highly Myopic Patients and Correlation with the Topography of Atrophic Maculopathy

IF 3.2 Q1 OPHTHALMOLOGY

Ophthalmology science Pub Date : 2025-02-19 DOI:10.1016/j.xops.2025.100743

Matteo Mario Carlà MD , Carlos Mateo MD

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Abstract

Purpose

To evaluate how the topography of atrophic patches influences monocular and binocular reading performances in eyes with pathologic myopia.

Design

Prospective single-center observational investigation.

Participants

Sixty-two patients (112 eyes) affected by pathologic myopia (axial length [AXL] >26.5 mm). Only college graduates aged <65 years were selected.

Methods

All patients underwent monocular and binocular reading evaluation using Colenbrander Reading Charts, taking into account the reading time and missed words/errors. Moreover, eyes underwent fundus photography and autofluorescence: the presence of chorioretinal atrophy within the central, 4 inner, and 4 outer ETDRS grid subfields was reviewed.

Main Outcome Measures

Reading acuity (logarithm of the reading acuity determination [logRAD]); reading speed (words per minute [wpm]); percentage of errors/missed word; correlation with ETDRS subfield atrophy localization.

Results

Mean AXL was 31.45 ± 2.21 mm. Monocularly, mean reading acuity was 0.37 ± 0.35 logRAD with an 8% ± 11% rate of missed or wrong words, whereas reading speed was 71.5 ± 27.8 wpm (range 25–125 wpm). Binocularly, mean reading acuity was 0.16 ± 0.16 logRAD with 5% ± 7% of missed or wrong words, whereas reading speed was 88.2 ± 18.0 wpm. Reading acuity was significantly associated with the presence of chorioretinal atrophy in the foveal central circle in univariate and multivariate analysis (P = 0.002). Conversely, reading speed negatively correlated with inner right subfield involvement in multivariate analysis (P = 0.008). Binocularly, reading acuity was associated with the presence of bilateral central atrophy (P = 0.001), whereas reading speed was associated with the presence of chorioretinal atrophy in the inner subfields on the horizontal plane in both eyes: bilateral inner right (P = 0.007) or inner left (P = 0.014) subfields; inner left OD (right eye)–inner right OS (left eye) (P = 0.002); inner right OD–inner left OS (P = 0.004).

Conclusions

In highly myopic eyes, we reported a significant relationship between the topography of patchy chorioretinal atrophy and reading performance.

Financial Disclosure(s)

The author(s) have no proprietary or commercial interest in any materials discussed in this article.

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高度近视患者阅读表现与萎缩性黄斑病变地形图的关系

目的探讨萎缩性眼斑地形对病理性近视患者单眼和双眼阅读能力的影响。前瞻性单中心观察性研究。参与者62例（112只眼）病理性近视（眼轴长度[AXL] >；26.5 mm）。只有年龄在65岁以上的大学毕业生入选。方法采用Colenbrander阅读量表对所有患者进行单眼和双眼阅读评估，同时考虑阅读时间和漏词/错误。此外，对眼睛进行眼底摄影和自身荧光检查：回顾了ETDRS中心、4个内、4个外网格子场中绒毛膜视网膜萎缩的存在。主要观察指标：阅读锐度（阅读锐度测定的对数[logRAD]）；阅读速度（每分钟字数[wpm]）；错误/漏词百分比；与ETDRS子场萎缩定位相关。结果平均AXL为31.45±2.21 mm。单眼平均阅读敏锐度为0.37±0.35 logRAD，漏词率为8%±11%，而阅读速度为71.5±27.8 wpm（范围25-125 wpm）。双眼平均阅读灵敏度为0.16±0.16 logRAD，漏词率为5%±7%，阅读速度为88.2±18.0 wpm。在单因素和多因素分析中，阅读灵敏度与中央凹中央圈绒毛膜视网膜萎缩存在显著相关（P = 0.002）。在多元分析中，阅读速度与右内子野涉入呈负相关（P = 0.008）。双眼，阅读敏度与双侧中枢萎缩相关（P = 0.001），而阅读速度与双眼水平面内亚野的绒毛视网膜萎缩相关：双侧右内亚野（P = 0.007）或左内亚野（P = 0.014）；左内OD（右眼）-右内OS（左眼）（P = 0.002）；内右od -内左OS （P = 0.004）。结论在高度近视眼中，斑片状绒毛膜视网膜萎缩的形貌与阅读能力有显著关系。财务披露作者在本文中讨论的任何材料中没有专有或商业利益。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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