Weak phospholipase-positive Listeria monocytogenes: a challenge for the diagnostic laboratory

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2025-03-14 DOI:10.1016/j.diagmicrobio.2025.116802

Marc J.A. Stevens , Joseph Wambui , Sabrina Corti , Magdalena Nüesch-Inderbinen , Roger Stephan

引用次数: 0

Abstract

Listeria monocytogenes isolates from environmental samples of a food producing company harboured a C424G mutation in the prfA gene that results in a G141A substitution in PrfA. This mutation results in strongly decreased phospholipase activity and is therefore challenging for culture-based detection of L. monocytogenes and may even lead to misidentification.

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弱磷脂酶阳性单核细胞增生李斯特菌：对诊断实验室的挑战

从一家食品生产公司的环境样本中分离出的单核细胞增生李斯特菌在prfA基因中含有C424G突变，导致prfA中的G141A替代。这种突变导致磷脂酶活性强烈降低，因此对基于培养的单核增生乳杆菌检测具有挑战性，甚至可能导致误认。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.