A quinolinium-based colorimetric and NIR fluorescent dual-channel sensing platform for specific detection of bisulfite in food, traditional Chinese medicine and living cells

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments Pub Date : 2025-03-17 DOI:10.1016/j.dyepig.2025.112767

Qiutong Chen , Jiaxing Li , Yiting Wang , Mingyu Tian , Tianyu Liang , Keli Zhong , Xiaomei Yan , Lijun Tang

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引用次数: 0

Abstract

Sulfur dioxide (SO₂) and its derivatives are commonly used in food processing, but excessive exposure to SO₂ and its derivatives can pose serious health risks. In this study, we present a near-infrared “turn-on” probe, QSB-M, for the highly selective and sensitive detection of HSO₃⁻. The recognition of HSO₃⁻ by the probe results in a marked color change and a significant enhancement in near-infrared fluorescence, offering high sensitivity (limit of detection = 95.12 nM), rapid response, and minimal interference from environmental background signals. The recognition mechanism involves the specific addition of HSO₃⁻ to the 4-position of the quinolinium moiety, triggering an intramolecular charge transfer effect that leads to both colorimetric and fluorescence dual responses. QSB-M was also successfully applied for in situ visualization of HSO₃⁻ in various foods and traditional Chinese medicines (TCM), with recoveries ranging from 90 % to 115 %. Additionally, test strips and a smartphone-assisted sensing platform were developed, enabling direct detection of HSO₃⁻ levels in foods and TCM without the need for complex instrumentation. Importantly, QSB-M exhibits low cytotoxicity, good mitochondrial-targeting ability, and has been successfully used for the in situ detection of both endogenous and exogenous HSO₃⁻ in live MCF-7 cells.

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来源期刊

Dyes and Pigments 工程技术-材料科学：纺织

CiteScore

8.20

自引率

13.30%

发文量

933

审稿时长

33 days

期刊介绍： Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied. Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media. The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.