Eman Samy Shalaby, Samy I Shalaby, Shaymaa A Ismail
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引用次数: 0
Abstract
The aim of this review is to highlight the role of semisolid systems as vehicles for nanovesicles and nanoparticles. In general, nanotechnology plays a critical role in facilitating the delivery of therapeutic agents to their active sites, and several nanocarrier systems have been explored for the topical administration of active components. The major disadvantage of the prepared nanosystems is their low viscosity, which reduces the time needed for enough absorption and negatively affects their stability and bioavailability. The role of semisolid systems is to overcome this limitation. In conclusion, this review presents an updated summary of recent advances in the use of semisolids as vehicles for various nanosystems through comprehensive scrutiny of the types of semisolids and their advantages and their role in enhancing the absorption of nanoparticles and nanovesicles.
期刊介绍：
Delivering therapeutics in a way that is right for the patient - safe, painless, reliable, targeted, efficient and cost effective - is the fundamental aim of scientists working in this area. Correspondingly, this evolving field has already yielded a diversity of delivery methods, including injectors, controlled release formulations, drug eluting implants and transdermal patches. Rapid technological advances and the desire to improve the efficacy and safety profile of existing medications by specific targeting to the site of action, combined with the drive to improve patient compliance, continue to fuel rapid research progress. Furthermore, the emergence of cell-based therapeutics and biopharmaceuticals such as proteins, peptides and nucleotides presents scientists with new and exciting challenges for the application of therapeutic delivery science and technology. Successful delivery strategies increasingly rely upon collaboration across a diversity of fields, including biology, chemistry, pharmacology, nanotechnology, physiology, materials science and engineering. Therapeutic Delivery recognizes the importance of this diverse research platform and encourages the publication of articles that reflect the highly interdisciplinary nature of the field. In a highly competitive industry, Therapeutic Delivery provides the busy researcher with a forum for the rapid publication of original research and critical reviews of all the latest relevant and significant developments, and focuses on how the technological, pharmacological, clinical and physiological aspects come together to successfully deliver modern therapeutics to patients. The journal delivers this essential information in concise, at-a-glance article formats that are readily accessible to the full spectrum of therapeutic delivery researchers.
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