Potential synergistic effects of microplastics and zinc oxide nanoparticles: biochemical and physiological analysis on Astacus leptodactylus.

IF 2.4 4区 环境科学与生态学 Q2 ECOLOGY
Mahdi Banaee, Amir Zeidi, Amin Gholamhosseini, Reza Shakeri, Caterina Faggio, Cristiana Roberta Multisanti
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引用次数: 0

Abstract

The present study aimed to evaluate the effects of microplastics (MPs) and Zinc Oxide nanoparticles (ZnO-NPs), both individually and in combination, on the crayfish, Astacus leptodactylus. A total of 360 crayfish were assigned to eight experimental groups, including control and treatment groups exposed to MPs (polyethylene, polystyrene, and polyvinyl chloride at 300 µg/L) and ZnO-NPs (5 µg/L), individually and combined. Biochemical analyses on the haemolymph revealed a significant increase in aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma glutamic transpeptidase activities, and glucose and cholesterol levels in crayfish exposed to MPs and ZnO-NPs. In contrast, butyrylcholinesterase activity was significantly decreased in all treatments compared to the control. Lactate dehydrogenase activity increased significantly in crayfish exposed to ZnO-NPs, alone or combined with MPs. Furthermore, thiol groups, total antioxidant levels, and glutathione peroxidase, glutathione reductase, catalase, and superoxide dismutase were significantly decreased, while malondialdehyde levels were increased. The integrated biomarker response (IBR) and radar plots highlighted a cumulative oxidative stress response, suggesting potential synergistic or additive interactions between MPs and ZnO-NPs.

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来源期刊
Ecotoxicology
Ecotoxicology 环境科学-毒理学
CiteScore
5.30
自引率
3.70%
发文量
107
审稿时长
4.7 months
期刊介绍: Ecotoxicology is an international journal devoted to the publication of fundamental research on the effects of toxic chemicals on populations, communities and terrestrial, freshwater and marine ecosystems. It aims to elucidate mechanisms and processes whereby chemicals exert their effects on ecosystems and the impact caused at the population or community level. The journal is not biased with respect to taxon or biome, and papers that indicate possible new approaches to regulation and control of toxic chemicals and those aiding in formulating ways of conserving threatened species are particularly welcome. Studies on individuals should demonstrate linkage to population effects in clear and quantitative ways. Laboratory studies must show a clear linkage to specific field situations. The journal includes not only original research papers but technical notes and review articles, both invited and submitted. A strong, broadly based editorial board ensures as wide an international coverage as possible.
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