The occurrence, concentration, and human health risk assessment of deoxynivalenol in beer: a global systematic review and meta-analysis.

IF 2.2 4区医学 Q3 ENVIRONMENTAL SCIENCES

International Journal of Environmental Health Research Pub Date : 2025-03-22 DOI:10.1080/09603123.2025.2482073

Denis A Nikolenko, Yadolah Fakhri, Fereshteh Mehri, Amirhossein Mahmoudizeh, Somayeh Dehghani, Behnam Khodadoust, Amin Mousavi Khaneghah

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Abstract

This study examined the concentration and occurrence of deoxynivalenol (DON) in beer and calculated the health risk to consumers using the target hazard quotient (THQ). The analysis considered the country and type of DON subgroups. Searches were performed in databases including Scopus, Web of Science, Embase, and PubMed from 1 January 2000, to 20 February 2024. Our study included 26 papers with 154 data reports. The rank order of DON types based on occurrence was DON (67.38%) > DON-3-Glc (61.45%) > DON-15-Ac (3.43%) > DON-3-Ac (2.58%). Based on concentration, DON (14.658 µg L⁻¹) > DON-3-Glc (14.190 µg L-1) > DON-15-Ac (13.023 µg L⁻¹) > DON-3-Ac (7.550 µg L⁻¹). The highest concentrations of DON, DON-3-Ac, DON-15-Ac, and DON-3-Glc in beer were observed in Cameroon (227.797 µg L⁻¹), Nigeria (27.000 µg L⁻¹), Nigeria (30.000 µg L⁻¹), and the Czech Republic (44.050 µg L⁻¹), respectively. The meta-regression reveals a significant decrease in the occurrence of DON in beer over time (C: -0.014; p-value = 0.016). Despite the higher health risk in Cameroon, Brazil, and Latvia compared to other countries, the health risk assessment revealed no significant non-carcinogenic risk for consumers.

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来源期刊

International Journal of Environmental Health Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.70

自引率

3.10%

发文量

134

审稿时长

>12 weeks

期刊介绍： International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.