Status of papillomacular bundle in optic disc pit associated with maculopathy.

IF 2.8 3区医学 Q1 OPHTHALMOLOGY

Eye Pub Date : 2025-03-21 DOI:10.1038/s41433-025-03761-x

Dmitrii S Maltsev, Alexei N Kulikov, Yana A Kalinicheva, Daniela Bacherini, Jay Chhablani

{"title":"Status of papillomacular bundle in optic disc pit associated with maculopathy.","authors":"Dmitrii S Maltsev, Alexei N Kulikov, Yana A Kalinicheva, Daniela Bacherini, Jay Chhablani","doi":"10.1038/s41433-025-03761-x","DOIUrl":null,"url":null,"abstract":"Purpose: To study the status of papillomacular bundle (PMB) in eyes with optic disc pit.Methods: Electronical medical records and optical coherence tomography (OCT) data of patients with optic disc pit were retrospectively reviewed. The PMB defect was measured on structural en face OCT projections. Length of ellipsoid zone defect (EZD) in the centre of the macula was measured on a horizontal cross-sectional scan passing through the centre of the fovea. Correlation between parameters under study, central retinal thickness (CRT), and visual acuity was calculated.Results: Thirteen eyes of thirteen patients (seven males and six females, mean age 31.3 ± 11.6 years) with optic disc pit and maculopathy and two eyes of two patients without maculopathy (2 females, 21 and 23 years) were included. The defect of PMB was found in 12 out 13 eyes (92.3%) with maculopathy. In those eyes EZD was found in 11 out of 13 eyes (84.6%). Among 12 eyes with PMB defect, 11 eyes had EZD (92.6%), one eye had PMB defect without EZD, while no eyes had EZD without PMB defect (p = 0.01). Mean PMB defect width was 0.86 ± 0.64 mm. Mean length of EZD was 425 ± 423 µm. The length of EZD and PMB width were highly correlated (r = 0.71, p < 0.001). Two eyes without maculopathy demonstrated no papillomacular bundle defect.Conclusion: Papillomacular bundle defect may be one of the essential characteristics in the optic disc pit with maculopathy and can be associated with the alteration of the central retina in these eyes.","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eye","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41433-025-03761-x","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To study the status of papillomacular bundle (PMB) in eyes with optic disc pit.

Methods: Electronical medical records and optical coherence tomography (OCT) data of patients with optic disc pit were retrospectively reviewed. The PMB defect was measured on structural en face OCT projections. Length of ellipsoid zone defect (EZD) in the centre of the macula was measured on a horizontal cross-sectional scan passing through the centre of the fovea. Correlation between parameters under study, central retinal thickness (CRT), and visual acuity was calculated.

Results: Thirteen eyes of thirteen patients (seven males and six females, mean age 31.3 ± 11.6 years) with optic disc pit and maculopathy and two eyes of two patients without maculopathy (2 females, 21 and 23 years) were included. The defect of PMB was found in 12 out 13 eyes (92.3%) with maculopathy. In those eyes EZD was found in 11 out of 13 eyes (84.6%). Among 12 eyes with PMB defect, 11 eyes had EZD (92.6%), one eye had PMB defect without EZD, while no eyes had EZD without PMB defect (p = 0.01). Mean PMB defect width was 0.86 ± 0.64 mm. Mean length of EZD was 425 ± 423 µm. The length of EZD and PMB width were highly correlated (r = 0.71, p < 0.001). Two eyes without maculopathy demonstrated no papillomacular bundle defect.

Conclusion: Papillomacular bundle defect may be one of the essential characteristics in the optic disc pit with maculopathy and can be associated with the alteration of the central retina in these eyes.

查看原文本刊更多论文

与黄斑病变相关的视盘窝乳头状斑束的状况。

目的：探讨视盘凹陷眼乳头状斑束（PMB）的状况。方法：回顾性分析视盘凹陷患者的电子病历和OCT资料。在结构表面OCT投影上测量PMB缺陷。通过中央凹中心的水平横断面扫描测量黄斑中心椭球区缺损（EZD）的长度。计算研究参数、中央视网膜厚度（CRT）与视力的相关性。结果：纳入视盘凹陷伴黄斑病变患者13例（男7例，女6例，平均年龄31.3±11.6岁）13只眼和无黄斑病变患者2例（女2例，21岁和23岁）2只眼。黄斑病变13只眼中有12只（92.3%）发现PMB缺损。13只眼中有11只眼出现EZD（84.6%）。PMB缺损12眼中有EZD 11眼（92.6%），PMB缺损无EZD 1眼，EZD无PMB缺损（p = 0.01）。PMB平均缺陷宽度为0.86±0.64 mm。平均EZD长度为425±423µm。结论：乳头状斑束缺损可能是黄斑病变视盘凹陷的基本特征之一，并可能与中央视网膜的改变有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Eye 医学-眼科学

CiteScore

6.40

自引率

5.10%

发文量

481

审稿时长

3-6 weeks

期刊介绍： Eye seeks to provide the international practising ophthalmologist with high quality articles, of academic rigour, on the latest global clinical and laboratory based research. Its core aim is to advance the science and practice of ophthalmology with the latest clinical- and scientific-based research. Whilst principally aimed at the practising clinician, the journal contains material of interest to a wider readership including optometrists, orthoptists, other health care professionals and research workers in all aspects of the field of visual science worldwide. Eye is the official journal of The Royal College of Ophthalmologists. Eye encourages the submission of original articles covering all aspects of ophthalmology including: external eye disease; oculo-plastic surgery; orbital and lacrimal disease; ocular surface and corneal disorders; paediatric ophthalmology and strabismus; glaucoma; medical and surgical retina; neuro-ophthalmology; cataract and refractive surgery; ocular oncology; ophthalmic pathology; ophthalmic genetics.