Enhancing Breeding Success Through Simple Intrauterine Insemination in Large-Scale Cynomolgus Macaque Colony

IF 2 3区 生物学 Q1 ZOOLOGY
Yong Lu, Lu Zhang, Yan Wang, Changshan Gao, Xinyan Bian, Yanhong Nie, Qiang Sun
{"title":"Enhancing Breeding Success Through Simple Intrauterine Insemination in Large-Scale Cynomolgus Macaque Colony","authors":"Yong Lu,&nbsp;Lu Zhang,&nbsp;Yan Wang,&nbsp;Changshan Gao,&nbsp;Xinyan Bian,&nbsp;Yanhong Nie,&nbsp;Qiang Sun","doi":"10.1002/ajp.70028","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Ultrasound-guided intrauterine insemination (IUI) has been successfully employed in cynomolgus macaques, yet its effectiveness in large-scale, multi-age cohorts has not been fully explored. Here, we implemented IUI within large breeding colonies to boost pregnancy rates in cynomolgus macaques. Ovulation timing was estimated by monitoring menstrual bleeding, after which IUI was performed. We then compared single menstrual cycle (SMC) pregnancy rates between IUI groups and harem-style mating groups. Our findings revealed that the overall pregnancy rate in the IUI group was significantly higher than in the harem-style breeding group across all ages. Notably, this advantage was mainly attributable to monkeys over 10 years old; in contrast, no significant difference was observed among 4–5-year-old and 6–10-year-old monkeys. Although pregnant females in the IUI group exhibited a higher birth rate compared to those in harem-style breeding, this difference was not statistically significant. Collectively, these results establish a basis for refining reproductive technologies in older cynomolgus macaque breeding programs and highlight potential improvements in managing large-scale colonies.</p></div>","PeriodicalId":7662,"journal":{"name":"American Journal of Primatology","volume":"87 3","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Primatology","FirstCategoryId":"99","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ajp.70028","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ZOOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Ultrasound-guided intrauterine insemination (IUI) has been successfully employed in cynomolgus macaques, yet its effectiveness in large-scale, multi-age cohorts has not been fully explored. Here, we implemented IUI within large breeding colonies to boost pregnancy rates in cynomolgus macaques. Ovulation timing was estimated by monitoring menstrual bleeding, after which IUI was performed. We then compared single menstrual cycle (SMC) pregnancy rates between IUI groups and harem-style mating groups. Our findings revealed that the overall pregnancy rate in the IUI group was significantly higher than in the harem-style breeding group across all ages. Notably, this advantage was mainly attributable to monkeys over 10 years old; in contrast, no significant difference was observed among 4–5-year-old and 6–10-year-old monkeys. Although pregnant females in the IUI group exhibited a higher birth rate compared to those in harem-style breeding, this difference was not statistically significant. Collectively, these results establish a basis for refining reproductive technologies in older cynomolgus macaque breeding programs and highlight potential improvements in managing large-scale colonies.

Abstract Image

求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
4.50
自引率
8.30%
发文量
103
审稿时长
4-8 weeks
期刊介绍: The objective of the American Journal of Primatology is to provide a forum for the exchange of ideas and findings among primatologists and to convey our increasing understanding of this order of animals to specialists and interested readers alike. Primatology is an unusual science in that its practitioners work in a wide variety of departments and institutions, live in countries throughout the world, and carry out a vast range of research procedures. Whether we are anthropologists, psychologists, biologists, or medical researchers, whether we live in Japan, Kenya, Brazil, or the United States, whether we conduct naturalistic observations in the field or experiments in the lab, we are united in our goal of better understanding primates. Our studies of nonhuman primates are of interest to scientists in many other disciplines ranging from entomology to sociology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信