Comparative study of simulation and experiment in determining 192Ir source strength for brachytherapy quality assurance

IF 2.8 3区物理与天体物理 Q3 CHEMISTRY, PHYSICAL

Radiation Physics and Chemistry Pub Date : 2025-03-18 DOI:10.1016/j.radphyschem.2025.112729

Tran Thi Bao Ngoc , Phan Quoc Uy , Le Quang Vuong , Tran Thien Thanh , Chau Van Tao

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引用次数: 0

Abstract

This research is of paramount importance as it combines experimental measurements and Monte Carlo simulation to determine the air kerma strength of the ¹⁹²Ir source, which plays a crucial role in dose calculations for brachytherapy treatment planning. The air kerma strength represents the source strength value, directly influencing the accuracy of dose calculations in cancer treatments. Verifying the source strength during each source exchange is essential to the quality assurance process.

In this study, the ¹⁹²Ir Gammamed Plus source, provided by Varian, was used to calculate the air kerma strength through experimental measurements and Monte Carlo simulation. The measurements were conducted on a brachytherapy system with an HDR 1000 Plus well-type ionization chamber and source tube 70010 from Standard Imaging. Using the MCNP6 code, we constructed a model equivalent to the experimental system, consisting of the source geometry, source tube, and well-type chamber, with source self-absorption also considered.

The air kerma strength measurements differed from the certified value by less than 2 %, within the allowable range according to the AAPM TG40 recommendations. The experimental and simulation methods showed strong agreement, with less than 4.1 % discrepancies. Considering source self-absorption, the air kerma strength calculation for the ¹⁹²Ir source was consistent across both methods. The findings of this study validate that we successfully built an experimental system model using the Monte Carlo simulation with the MCNP6 code. This model can be further developed for future research.

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来源期刊

Radiation Physics and Chemistry 化学-核科学技术

CiteScore

5.60

自引率

17.20%

发文量

574

审稿时长

12 weeks

期刊介绍： Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.