Severe Complicated Secondary Antiphospholipid Syndrome Conjointly with Systemic Lupus Erythematosus - Case Report.

Sonja Vidinikj, Dubravka Antova, Maja Bojadzioska, Filip Gucev, Emilija Sandevska, Anzelika Karadzova-Stojanovska, Sonja Pavlova, Ana Vasilevska, Ivan Vidinikj, Ron Vejseli
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Abstract

Antiphospholipid syndrome (APS), is an autoimmune systemic disorder known to manifest with thrombosis in almost all vessels throughout the body, can also be accompanied by pregnancy morbidity, and is persistent with the presence of antiphospholipid antibodies, including lupus anticoagulant antibodies, or relatively high titers of anticardiolipin, or anti-β2Glycoprotein I antibodies. APS can occur alone or in association with other diseases, more commonly systemic lupus erythematous. In patients with both underlying diseases episodes of arthritis, skin changes in the form of livedo reticularis, thrombocytopenia and leucopenia were more common. Cardiac manifestations have also been reported. Here we present a complicated case of a young female patient with antiphospholipid syndrome and an underlying systemic lupus erythematosus.

严重并发继发性抗磷脂综合征合并系统性红斑狼疮--病例报告。
抗磷脂综合征(APS)是一种自身免疫性全身性疾病,已知表现为全身几乎所有血管的血栓形成,也可伴有妊娠并发症,并且持续存在抗磷脂抗体,包括狼疮抗凝抗体,或相对高滴度的抗心磷脂或抗β2糖蛋白I抗体。APS可单独发生或与其他疾病相关,更常见的是系统性红斑狼疮。在患有关节炎的两种基础疾病的患者中,网状斑点、血小板减少和白细胞减少等形式的皮肤变化更为常见。心脏表现也有报道。这里我们提出一个复杂的情况下,年轻的女性患者抗磷脂综合征和潜在的系统性红斑狼疮。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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