ALA-PDT for a male deep urethral condyloma acuminatum

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-03-19 DOI:10.1016/j.pdpdt.2025.104557

Rongjie Zuo , Yimin He , Huan Liu, Fang Wu, Xiuling Li, Hui Wan, Ying Gao

引用次数: 0

Abstract

Condyloma acuminata (CA) is one of the most common sexually transmitted diseases caused by human papillomavirus (HPV) infection. 5-aminolevulinic acid (ALA)-based photodynamic therapy has shown good efficacy in the treatment of HPV-related diseases . In recent years, the incidence of male urethral condyloma acuminata (MUCA) has been gradually increasing. However, due to its hidden and special anatomical structure, diagnosis and treatment pose a major challenge in clinical practice. In this report, photodynamic therapy combined with thulium laser achieved a sufficient effect on MUCA. We made an injector modifying a ureteral catheter to make the 5-aminolevulinic acid (ALA) gel reach the treatment depth in the urethra. And there was no recurrence during the 2-year follow-up period.

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ALA-PDT 治疗男性深尿道尖锐湿疣。

尖锐湿疣（CA）是由人乳头瘤病毒（HPV）感染引起的最常见的性传播疾病之一。以5-氨基乙酰丙酸（ALA）为基础的光动力疗法在hpv相关疾病的治疗中显示出良好的疗效。近年来，男性尿道尖锐湿疣（MUCA）的发病率逐渐上升。但由于其隐蔽性和特殊的解剖结构，给临床诊断和治疗带来了很大的挑战。在本报告中，光动力疗法联合铥激光治疗MUCA取得了足够的效果。我们制作了一种改良输尿管导管的注射器，使5-氨基乙酰丙酸（ALA）凝胶在尿道内达到治疗深度。随访2年无复发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.