PSMA PET in Management of Vestibular Schwannoma.

IF 3.4 3区 医学 Q2 ONCOLOGY
Pavnesh Kumar, Kyle Wu, Daniel Prevedello, Edward Dodson, Jana Ivanidze, Divya Yadav, Rituraj Upadhyay, Jonathan P S Knisely, Oliver Adunka, TaeLor Jones, Evan M Thomas, Raju R Raval, Sasha Beyer, Bingfeng Tang, Joshua D Palmer
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引用次数: 0

Abstract

Vestibular Schwannomas (VS) are benign tumors arising from vestibulocochlear nerve Schwann cells. Single or multifractional stereotactic radiation therapy (SRT) is commonly used for treatment of these tumors and accurate target delineation is critical for the focused radiation delivery, maximizing tumor control while minimizing toxicity. Contrast-enhanced MRI is the gold standard for diagnosis, monitoring of VS and is critical in precise target delineation for SRT planning. Prostate Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) has established clinical utility for diagnosis and monitoring of prostate cancer. However other central nervous system neoplasms including VS have also been found to be PSMA tracer avid. We present the first clinical use of PSMA PET for SRT in a patient with VS who was unable to undergo MRI.

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来源期刊
Practical Radiation Oncology
Practical Radiation Oncology Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
5.20
自引率
6.10%
发文量
177
审稿时长
34 days
期刊介绍: The overarching mission of Practical Radiation Oncology is to improve the quality of radiation oncology practice. PRO''s purpose is to document the state of current practice, providing background for those in training and continuing education for practitioners, through discussion and illustration of new techniques, evaluation of current practices, and publication of case reports. PRO strives to provide its readers content that emphasizes knowledge "with a purpose." The content of PRO includes: Original articles focusing on patient safety, quality measurement, or quality improvement initiatives Original articles focusing on imaging, contouring, target delineation, simulation, treatment planning, immobilization, organ motion, and other practical issues ASTRO guidelines, position papers, and consensus statements Essays that highlight enriching personal experiences in caring for cancer patients and their families.
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