Sentinel lymph node biopsy in gynecological malignancies: A modern approach to surgical staging - A narrative review.

IF 3.5 2区 医学 Q2 ONCOLOGY
Ejso Pub Date : 2025-03-14 DOI:10.1016/j.ejso.2025.109757
Aleksandar Celebic, Mirjana Miladinovic, Marina Jakimovska Stefanovska, Jean Calleja Agius, Kristina Drusany Staric
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引用次数: 0

Abstract

Sentinel lymph node biopsy (SLNB) has emerged as a valuable alternative to traditional lymphadenectomy in the surgical management of gynecological cancers. This narrative review delves into the advantages, practical applications, and future research directions of SLNB in this context. Compared to the more extensive lymphadenectomy, SLNB offers a minimally invasive approach to lymph node staging, leading to reduced surgical morbidity, faster recovery times, and improved quality of life for the patients involved. This narrative review highlights the high detection rates and accuracy of SLNB in predicting lymph node metastasis, particularly in early-stage endometrial, cervical and vulvar cancers. By accurately assessing lymph node status, SLNB provides crucial information for treatment planning, potentially guiding decisions regarding adjuvant therapies and assessing the need for further lymph node dissection. From clinical practice guidelines, prospective studies, and relevant research articles, this review provides a thorough understanding the evolving role of SLNB in managing gynecological malignancies. The findings presented underscore the potential of SLNB to improve patient outcomes by providing accurate staging while minimizing surgical complications.

在妇科癌症的外科治疗中,前哨淋巴结活检(SLNB)已成为传统淋巴结切除术的重要替代方法。本综述将深入探讨前哨淋巴结活检的优势、实际应用和未来研究方向。与范围更广的淋巴结切除术相比,SLNB 提供了一种微创的淋巴结分期方法,可降低手术发病率、缩短恢复时间并提高相关患者的生活质量。这篇叙述性综述强调了 SLNB 在预测淋巴结转移方面的高检出率和准确性,尤其是在早期子宫内膜癌、宫颈癌和外阴癌中。通过准确评估淋巴结状态,SLNB 为治疗计划提供了重要信息,有可能为辅助治疗决策提供指导,并评估进一步淋巴结清扫的必要性。从临床实践指南、前瞻性研究和相关研究文章中,本综述全面介绍了 SLNB 在妇科恶性肿瘤治疗中不断发展的作用。这些研究结果强调了 SLNB 的潜力,即在提供准确分期的同时最大限度地减少手术并发症,从而改善患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Ejso
Ejso 医学-外科
CiteScore
6.40
自引率
2.60%
发文量
1148
审稿时长
41 days
期刊介绍: JSO - European Journal of Surgical Oncology ("the Journal of Cancer Surgery") is the Official Journal of the European Society of Surgical Oncology and BASO ~ the Association for Cancer Surgery. The EJSO aims to advance surgical oncology research and practice through the publication of original research articles, review articles, editorials, debates and correspondence.
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