Trends and Disparities in Diabetes Mellitus and Atrial fibrillation Related Mortality in the United States: 1999–2020

IF 6.1 3区医学 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes research and clinical practice Pub Date : 2025-03-19 DOI:10.1016/j.diabres.2025.112112

Muhammad Umer Sohail , Taimor Mohammed Khan , Maryam Sajid , Zahra Imran , Hussain Salim , Saad Ahmed Waqas , Sebastian Mactaggart , Raheel Ahmed

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Abstract

The co-occurrence of diabetes mellitus (DM) and atrial fibrillation (AF) poses growing health risks in the United States (U.S.), with diabetes patients having a 34 % higher risk of AF. This study examines trends in DM and AF related mortality among individuals aged ≥ 25 years in the U.S. from 1999 to 2020. Data from the CDC WONDER database were analyzed calculating age-adjusted mortality rates (AAMRs) per 100,000 and annual percent change (APC), stratified by age, sex, race/ethnicity, urbanization, and region. Between 1999 and 2020, 419,036 deaths were recorded among U.S. adults (≥25 years) with comorbid AF and DM. The AAMR rose from 4.83 in 1999 to 15.91 in 2020, with an APC increase of 15.01 from 2018 to 2020. Older adults (≥65) had higher AAMRs than younger adults (25–64). Men (11.23) had higher rates than women (7.16). NH American Indian/Alaskan Natives (9.54) and Whites (9.16) had the highest AAMRs, while NH Asian/Pacific Islanders (6.04) had the lowest. Non-metropolitan areas (10.32) exceeded metropolitan areas (8.53). The Western U.S. (9.87) had the highest regional AAMR. Rising DM and AF-related deaths highlight a growing burden, particularly in men, NH American Indian/Alaskan Natives and Whites, and rural populations, necessitating targeted interventions.

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美国糖尿病和心房颤动相关死亡率的趋势和差异：1999-2020.

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来源期刊

Diabetes research and clinical practice 医学-内分泌学与代谢

CiteScore

10.30

自引率

3.90%

发文量

862

审稿时长

32 days

期刊介绍： Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.