Camehakosides A-E, Five Undescribed Acylated Oleanane Saponins from the Leaves of Camellia hakodae with Their α-Glucosidase Inhibitory Activity.

IF 2.3 3区化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Chemistry & Biodiversity Pub Date : 2025-03-21 DOI:10.1002/cbdv.202500694

Pham Hai Yen, Nguyen Thi Cuc, Duong Thi Dung, Do Thi Trang, Ngo Anh Bang, Nguyen Viet Dung, Dan Thi Thuy Hang, Nguyen Huy Hoang, Phan Thi Thanh Huong, Bui Huu Tai, Phan Van Kiem

引用次数: 0

Abstract

Five undescribed acylated oleanane saponins (1-5), together with five known compounds (6-10) were isolated from the leaves of Camellia hakodae. Their chemical structures were determined by IR, HR-ESI-MS, 1D, and 2D NMR spectra. Compounds 1-10 significantly inhibited α-glucosidase with IC50 values ranging from 2.11 ± 0.18 to 10.42 ± 0.41 µM.

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来源期刊

Chemistry & Biodiversity 环境科学-化学综合

CiteScore

3.40

自引率

10.30%

发文量

475

审稿时长

2.6 months

期刊介绍： Chemistry & Biodiversity serves as a high-quality publishing forum covering a wide range of biorelevant topics for a truly international audience. This journal publishes both field-specific and interdisciplinary contributions on all aspects of biologically relevant chemistry research in the form of full-length original papers, short communications, invited reviews, and commentaries. It covers all research fields straddling the border between the chemical and biological sciences, with the ultimate goal of broadening our understanding of how nature works at a molecular level. Since 2017, Chemistry & Biodiversity is published in an online-only format.