Linked empirical studies reveal the cumulative impact of acquired tick resistance across the tick life cycle

IF 3.1 2区 医学 Q2 INFECTIOUS DISEASES
J.P. Owen , A. Gibbs , C.R. Jones , J.L. Brunner , K. Mason , S.M. Noh , G.A. Scoles
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引用次数: 0

Abstract

Host defenses affect tick feeding success, and thus survival and reproduction, but defensive traits have rarely been studied relative to tick population dynamics. We explored the effects of anti-tick resistance of three natural hosts against Dermacentor andersoni, the Rocky Mountain wood tick. Larval ticks were fed on Deer mice (Peromyscus maniculatus) and Cottontail rabbits (Sylvilagus nuttallii), and nymph and adult ticks were fed on cattle (Bos taurus). We compared feeding success and fecundity of ticks fed on naïve (never infested by ticks) or exposed (one prior tick infestation) hosts. We used these measures to parameterize simulations of D. andersoni population growth in a discrete time, geometric population model to understand the population-level consequences of anti-tick resistance. Prior infestation triggered tick resistance in all three host species and impacted all tick life stages. On tick-exposed hosts, an average of 23 % fewer ticks reached adulthood and adult females produced 32 % fewer larvae. Modest effects of tick resistance at each life stage had strong cumulative effects across the tick life cycle. Simulated tick population dynamics revealed that mean population growth (λ) is reduced 68 % when the life cycle is completed on hosts with prior tick exposure. Simulated populations feeding on exposed hosts were more likely to decline (λ<1) under conditions of low off-host survival and host-finding. This suggests acquired tick resistance may interact with environmental conditions and host availability to affect tick population dynamics. These data shed new light on naturally occurring biotic factors that may affect tick abundance and tick-borne pathogen transmission.
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来源期刊
Ticks and Tick-borne Diseases
Ticks and Tick-borne Diseases INFECTIOUS DISEASES-MICROBIOLOGY
CiteScore
6.90
自引率
12.50%
发文量
185
审稿时长
6-12 weeks
期刊介绍: Ticks and Tick-borne Diseases is an international, peer-reviewed scientific journal. It publishes original research papers, short communications, state-of-the-art mini-reviews, letters to the editor, clinical-case studies, announcements of pertinent international meetings, and editorials. The journal covers a broad spectrum and brings together various disciplines, for example, zoology, microbiology, molecular biology, genetics, mathematical modelling, veterinary and human medicine. Multidisciplinary approaches and the use of conventional and novel methods/methodologies (in the field and in the laboratory) are crucial for deeper understanding of the natural processes and human behaviour/activities that result in human or animal diseases and in economic effects of ticks and tick-borne pathogens. Such understanding is essential for management of tick populations and tick-borne diseases in an effective and environmentally acceptable manner.
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