Genital Psoriasis in Asians: Impact on Quality of Life and Sexual Health

IF 3.5 3区医学 Q1 DERMATOLOGY

Experimental Dermatology Pub Date : 2025-03-20 DOI:10.1111/exd.70072

Kim Yao Ong, Yee Kiat Heng, Xiahong Zhao, Hazel H. Oon

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Abstract

Genital involvement and sexual dysfunction are common amongst patients with psoriasis. However, the effects of genital psoriasis on quality of life (QOL) and sexual health of psoriasis patients are not well understood. We performed an observational study on adult Asian psoriasis patients attending psoriasis subspecialty clinics in a tertiary dermatology centre in Singapore over 1 year. Participants underwent clinical examination of the whole-body surface, with particular attention to the genitalia and questionnaires to evaluate QOL and psychosexual health were administered. A total of 62 patients participated. Most participants were male (82.3%) with a mean age of 41.7 years (SD 12.5). The mean Psoriasis Area and Severity Index (PASI) score was 7.0 (SD 4.3) with a mean Dermatology Life Quality Index (DLQI) score of 9.8 (SD 6.7), indicating moderately impaired QOL. Higher PASI scores were associated with increasing QOL impairment on DLQI (p = 0.021). The commonest site involved was the suprapubic region (61.3%). Males in whom genital psoriasis prevented sexual intercourse or diminished their libido reported more sexual dysfunction. Females reported a greater severity impact of genital psoriasis in terms of symptoms and embarrassment (p = 0.038) yet were less likely to be on treatment (37.5% vs. 45.0%). Perceived efficacy of treatment was low, and younger patients fared poorly on the Patient Health Questionnaire-9 depression questionnaire (p = 0.047). Clinicians should proactively evaluate for and treat genital psoriasis, as patients may be reluctant to discuss their genital rashes if not prompted, leading to under-recognition and undertreatment.

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亚洲人生殖器牛皮癣：对生活质量和性健康的影响。

生殖器受累和性功能障碍在牛皮癣患者中很常见。然而，生殖器银屑病对银屑病患者生活质量（QOL）和性健康的影响尚不清楚。我们对在新加坡三级皮肤科中心的银屑病亚专科诊所就诊1年以上的成年亚洲银屑病患者进行了一项观察性研究。参与者接受了全身体表的临床检查，特别关注生殖器，并进行了评估生活质量和性心理健康的问卷调查。共有62名患者参与。大多数参与者为男性（82.3%），平均年龄为41.7岁（SD 12.5）。平均银屑病面积和严重程度指数（PASI）评分为7.0 (SD 4.3)，平均皮肤病生活质量指数（DLQI）评分为9.8 (SD 6.7)，表明生活质量中度受损。PASI得分越高，DLQI的生活质量损害越严重（p = 0.021）。最常见的受累部位为耻骨上区（61.3%）。生殖器牛皮癣导致性交受阻或性欲减退的男性报告了更多的性功能障碍。女性在症状和尴尬方面报告了更严重的生殖器牛皮癣影响（p = 0.038），但较少接受治疗（37.5%对45.0%）。感知治疗效果低，年轻患者在患者健康问卷-9抑郁问卷上表现较差（p = 0.047）。临床医生应积极评估和治疗生殖器牛皮癣，因为如果没有提示，患者可能不愿意讨论他们的生殖器皮疹，导致认识不足和治疗不足。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Experimental Dermatology 医学-皮肤病学

CiteScore

6.70

自引率

5.60%

发文量

201

审稿时长

2 months

期刊介绍： Experimental Dermatology provides a vehicle for the rapid publication of innovative and definitive reports, letters to the editor and review articles covering all aspects of experimental dermatology. Preference is given to papers of immediate importance to other investigators, either by virtue of their new methodology, experimental data or new ideas. The essential criteria for publication are clarity, experimental soundness and novelty. Letters to the editor related to published reports may also be accepted, provided that they are short and scientifically relevant to the reports mentioned, in order to provide a continuing forum for discussion. Review articles represent a state-of-the-art overview and are invited by the editors.