Metal-free amination of alkenes based on maleimides†

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-03-13 DOI:10.1039/D5OB00201J

Li-Wen Shen, Shuang-Ling Lei, Hong-Yan Wang, Xin Wang, Lin-Mu Lu, Guang-Wei Wang, Yun-Qing Jia and Min Xiang

引用次数: 0

Abstract

A metal-free amination of alkenes based on maleimides has been developed. This method features mild reaction conditions and broad substrate scope, and aminomaleimides with EWGs have been synthesized in up to 99% yield. The gram-scale reaction and successful derivatization of the products further demonstrate the applicability of this methodology.

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我们开发了一种基于马来酰亚胺的烯烃无金属胺化方法。该方法具有反应条件温和、底物范围广的特点，并能合成具有 EWGs 的氨基马来酰亚胺，收率高达 99%。克级反应和产物的成功衍生进一步证明了该方法的适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.