Bismuth vanadate modified glassy carbon electrode for sensitive electrochemical antibiotic detection

IF 2.1 4区材料科学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Journal of Nanoparticle Research Pub Date : 2025-03-21 DOI:10.1007/s11051-025-06280-8

Timmy Unya Anak Nedy, Mohammad Aliff bin Ali Rahman, Ellie Yi Lih Teo, Pang Hung Yiu, Elisha Yiu, Alvin Lim Teik Zheng, Yoshito Andou

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Abstract

This study presents the successful synthesis of bismuth vanadate (BiVO₄) using a hydrothermal method and its application as a modifier on glassy carbon electrode (GCE). Fourier-transform infrared (FTIR) spectroscopy confirmed the presence of V–O stretching vibrations, while X-ray diffraction (XRD) analysis verified a pure monoclinic BiVO₄ crystal structure. Morphological analysis revealed spherical BiVO₄ particles, which contributed to enhanced electrochemical performance when integrated into the modified GCE. BiVO₄/GCE exhibited superior electrochemical performance, as confirmed by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) studies, in detecting analytes including hexacyanoferrate, tetracycline (TC), and levofloxacin (LVX). BiVO₄ modification significantly boosted the performance of the electrode in terms of sensitivity, selectivity, and electron transfer kinetics. These enhancements can be attributed to BiVO₄’s efficient electron transport and electrocatalytic activity. Notably, BiVO₄/GCE exhibited the potential for simultaneous detection of multiple antibiotics showing its versatility for diverse electrochemical sensing applications. The limits of detection (LOD) and quantification (LOQ) for TC were 27.9 µM and 83.3 µM, respectively, while for LVX, they were 7.39 µM and 22.3 µM. Overall, these findings position BiVO₄/GCE as a promising platform for advanced electrochemical detection and analysis across various fields.

Graphical Abstract

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本研究采用水热法成功合成了钒酸铋（BiVO4），并将其用作玻璃碳电极（GCE）的改性剂。傅立叶变换红外光谱（FTIR）证实了 V-O 伸展振动的存在，而 X 射线衍射（XRD）分析则验证了纯单斜 BiVO4 晶体结构。形态分析表明，BiVO4 颗粒呈球形，与改性 GCE 集成后，电化学性能得到增强。循环伏安法（CV）和微分脉冲伏安法（DPV）研究证实，BiVO4/GCE 在检测包括六氰基铁酸酯、四环素（TC）和左氧氟沙星（LVX）在内的分析物时表现出卓越的电化学性能。在灵敏度、选择性和电子转移动力学方面，BiVO4 修饰都大大提高了电极的性能。这些改进可归功于 BiVO4 的高效电子传输和电催化活性。值得注意的是，BiVO4/GCE 具有同时检测多种抗生素的潜力，这表明它在多种电化学传感应用方面具有多功能性。TC 的检出限（LOD）和定量限（LOQ）分别为 27.9 µM 和 83.3 µM，而 LVX 的检出限（LOD）和定量限（LOQ）分别为 7.39 µM 和 22.3 µM。总之，这些研究结果将 BiVO4/GCE 定位为在各个领域进行先进电化学检测和分析的理想平台。

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来源期刊

Journal of Nanoparticle Research 工程技术-材料科学：综合

CiteScore

4.40

自引率

4.00%

发文量

198

审稿时长

3.9 months

期刊介绍： The objective of the Journal of Nanoparticle Research is to disseminate knowledge of the physical, chemical and biological phenomena and processes in structures that have at least one lengthscale ranging from molecular to approximately 100 nm (or submicron in some situations), and exhibit improved and novel properties that are a direct result of their small size. Nanoparticle research is a key component of nanoscience, nanoengineering and nanotechnology. The focus of the Journal is on the specific concepts, properties, phenomena, and processes related to particles, tubes, layers, macromolecules, clusters and other finite structures of the nanoscale size range. Synthesis, assembly, transport, reactivity, and stability of such structures are considered. Development of in-situ and ex-situ instrumentation for characterization of nanoparticles and their interfaces should be based on new principles for probing properties and phenomena not well understood at the nanometer scale. Modeling and simulation may include atom-based quantum mechanics; molecular dynamics; single-particle, multi-body and continuum based models; fractals; other methods suitable for modeling particle synthesis, assembling and interaction processes. Realization and application of systems, structures and devices with novel functions obtained via precursor nanoparticles is emphasized. Approaches may include gas-, liquid-, solid-, and vacuum-based processes, size reduction, chemical- and bio-self assembly. Contributions include utilization of nanoparticle systems for enhancing a phenomenon or process and particle assembling into hierarchical structures, as well as formulation and the administration of drugs. Synergistic approaches originating from different disciplines and technologies, and interaction between the research providers and users in this field, are encouraged.