[Systemic therapy of atopic dermatitis and psoriasis in children and adolescents].

Dermatologie (Heidelberg, Germany) Pub Date : 2025-04-01 Epub Date: 2025-03-19 DOI:10.1007/s00105-025-05486-0
Michael Sticherling
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Abstract

Psoriasis and atopic dermatitis are among the most frequent chronic, inflammatory skin diseases of childhood and adolescence. Regarding profound consequences for the physical and psychosocial development of affected patients, a timely and individually adapted therapy has to be initiated, in case of severe disease systemic treatment. Modern, targeted, highly efficient and well-tolerated agents are currently available. Overlapping psoriasis and atopic dermatitis have been appreciated recently, both idiopathic and therapeutically induced. Their prevention or early detection is mandatory for optimal management of patients.

[儿童和青少年特应性皮炎和银屑病的全身治疗]。
牛皮癣和特应性皮炎是儿童和青少年最常见的慢性炎症性皮肤病。关于对受影响患者的生理和心理发展产生的深远影响,在严重的疾病进行全身治疗的情况下,必须开始及时和个别适应的治疗。现代、有针对性、高效且耐受性良好的药物目前已经可用。重叠银屑病和特应性皮炎最近得到了重视,无论是特发性的还是治疗性的。它们的预防或早期发现是对患者进行最佳管理的必要条件。
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