Austrida Gondwe, Effie Chipeta, Mina C Hosseinipour, Bridon Mbaya, Adamson S Muula, Victor Mwapasa, Patani Mhango, Princess Kaira, Tiyamike Nthani, Sydney Puerto-Meredith, Natasha Nsamala, Emmanuel Singogo
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引用次数: 0
Abstract
Background and objectives: In many countries, including Africa, the widespread gap between national blood requirements and actual blood supplies contributes to unnecessary deaths. This scoping review explores common facilitators and barriers to blood donation in sub-Saharan Africa (SSA) and strategies that are used to increase and maintain repeat blood donation.
Materials and methods: We conducted a scoping review of facilitators and barriers to blood donation in SSA. We searched PubMed, Ovid MEDLINE, Ovid EMBASE and COCHRANE to identify relevant papers. Of the 2225 articles screened by title, abstract and papers published after 2010, 37 were included in the final full-text screening. Article quality for inclusion was assessed on the basis of a predefined eligibility and inclusion checklist. We analysed all papers that reported barriers and facilitators to blood donation in Africa.
Results: The review included 11 studies. The common facilitators for blood donation reported were altruism, the opportunity for disease testing, friendly recruitment strategies and future easy access to blood at hospitals when needed. We identified the following barriers: lack of knowledge, awareness of blood donation and place of donation, fear, ineffective incentives, bad service experiences and religious and cultural beliefs.
Conclusion: Findings of this review can be used to propose better strategies for improving blood donation in SSA. Strategies that encourage blood donation can be leveraged and implemented, while those that discourage blood donation can be adapted to better achieve an adequate supply.
期刊介绍：
Vox Sanguinis reports on important, novel developments in transfusion medicine. Original papers, reviews and international fora are published on all aspects of blood transfusion and tissue transplantation, comprising five main sections:
1) Transfusion - Transmitted Disease and its Prevention:
Identification and epidemiology of infectious agents transmissible by blood;
Bacterial contamination of blood components;
Donor recruitment and selection methods;
Pathogen inactivation.
2) Blood Component Collection and Production:
Blood collection methods and devices (including apheresis);
Plasma fractionation techniques and plasma derivatives;
Preparation of labile blood components;
Inventory management;
Hematopoietic progenitor cell collection and storage;
Collection and storage of tissues;
Quality management and good manufacturing practice;
Automation and information technology.
3) Transfusion Medicine and New Therapies:
Transfusion thresholds and audits;
Haemovigilance;
Clinical trials regarding appropriate haemotherapy;
Non-infectious adverse affects of transfusion;
Therapeutic apheresis;
Support of transplant patients;
Gene therapy and immunotherapy.
4) Immunohaematology and Immunogenetics:
Autoimmunity in haematology;
Alloimmunity of blood;
Pre-transfusion testing;
Immunodiagnostics;
Immunobiology;
Complement in immunohaematology;
Blood typing reagents;
Genetic markers of blood cells and serum proteins: polymorphisms and function;
Genetic markers and disease;
Parentage testing and forensic immunohaematology.
5) Cellular Therapy:
Cell-based therapies;
Stem cell sources;
Stem cell processing and storage;
Stem cell products;
Stem cell plasticity;
Regenerative medicine with cells;
Cellular immunotherapy;
Molecular therapy;
Gene therapy.
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