Strain Elastography: A Non-Invasive Modality for Extrathyroidal Extension Assessment in Papillary Thyroid Cancer.

IF 1.2 4区医学 Q3 ACOUSTICS

Journal of Clinical Ultrasound Pub Date : 2025-03-20 DOI:10.1002/jcu.23970

Huahui Liu, Shuang Liang, Shiwen Zhang, Xiaodan Zhang, Liping Luo, Ying Liu, Xi Zhou, Sainan Guan, Wanling Huang, Cai Hu, Lingli Xiao, Shuguang Liu, Ronghua Yan, Erjiao Xu

引用次数: 0

Abstract

This study investigated the value of strain elastography (SE) in assessing extrathyroidal extension (ETE) in papillary thyroid cancer (PTC). A total of 277 PTC nodules from 245 patients were included. SE demonstrated higher consistency with pathology compared to US (Kappa value: 0.735 vs. 0.562, p = 0.000, respectively). SE also showed superior specificity (91.4% vs. 74.1%, p = 0.000) and accuracy (87.7% vs. 78.3%, p = 0.003) in diagnosing ETE. The area under the curve for SE was significantly higher than for US (0.865 vs. 0.798, p = 0.006). Age and calcification influenced SE's diagnostic performance. SE is a promising noninvasive tool for ETE assessment in PTC.

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来源期刊

Journal of Clinical Ultrasound 医学-核医学

CiteScore

1.90

自引率

0.00%

发文量

248

审稿时长

6 months

期刊介绍： The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography. The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents. JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.