{"title":"A Manual Technique for Corneal Allogeneic Intrastromal Ring Segments Without a Femtosecond Laser.","authors":"Takahiko Hayashi, Yusuke Hara, Chihiro Sunouchi, Kentaro Yuda, Takashi Kojima, Naoko Kato, Brendan Cronin, Satoru Yamagami","doi":"10.1097/ICO.0000000000003853","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the outcomes of corneal allogeneic intrastromal ring segments (CAIRS) using a simplified manual technique for treating keratoconus.</p><p><strong>Methods: </strong>This prospective case series included 5 eyes from 5 patients with keratoconus (4 males, 1 female, mean age 32.5 ± 10.6 years) treated with manual CAIRS. Surgeries were performed under local anesthesia by a single surgeon. An intrastromal pocket for donor tissue implantation was manually created using a spatula, and donor corneas were prepared using a Jacobs CAIRS trephine. Corneal parameters, including higher-order aberrations, coma, and spherical aberrations at a 6 mm diameter, were measured using optical coherence tomography (CASIA SS-1000, Tomey, Japan). Anterior and posterior corneal indices, subjective refractive power, cylinder, spherical equivalent, best-corrected visual acuity (BCVA; logarithm of the minimum angle of resolution [logMAR]), and central corneal thickness. Intra- and postoperative complications were also analyzed.</p><p><strong>Results: </strong>Over a mean follow-up of 6.4 ± 2.9 months, no complications occurred. BCVA improved from 0.74 ± 0.44 logMAR preoperatively to 0.19 ± 0.66 logMAR (P = 0.043). The maximum keratometry (Kmax) value decreased from 63.6 ± 8.3D preoperatively to 59.6 ± 6.8D postoperatively (P = 0.043). Spherical equivalent improved from -11.2 ± 5.8D to -5.3 ± 3.1D (P = 0.043), and astigmatism reduced from -5.0 ± 3.4D to -3.3 ± 2.9D. Total corneal higher-order aberrations decreased from 5.6 ± 1.6D to 4.2 ± 1.6D postoperatively (P = 0.043).</p><p><strong>Conclusions: </strong>Manual CAIRS is an effective treatment when a femtosecond laser is not available.</p>","PeriodicalId":10710,"journal":{"name":"Cornea","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cornea","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/ICO.0000000000003853","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To evaluate the outcomes of corneal allogeneic intrastromal ring segments (CAIRS) using a simplified manual technique for treating keratoconus.
Methods: This prospective case series included 5 eyes from 5 patients with keratoconus (4 males, 1 female, mean age 32.5 ± 10.6 years) treated with manual CAIRS. Surgeries were performed under local anesthesia by a single surgeon. An intrastromal pocket for donor tissue implantation was manually created using a spatula, and donor corneas were prepared using a Jacobs CAIRS trephine. Corneal parameters, including higher-order aberrations, coma, and spherical aberrations at a 6 mm diameter, were measured using optical coherence tomography (CASIA SS-1000, Tomey, Japan). Anterior and posterior corneal indices, subjective refractive power, cylinder, spherical equivalent, best-corrected visual acuity (BCVA; logarithm of the minimum angle of resolution [logMAR]), and central corneal thickness. Intra- and postoperative complications were also analyzed.
Results: Over a mean follow-up of 6.4 ± 2.9 months, no complications occurred. BCVA improved from 0.74 ± 0.44 logMAR preoperatively to 0.19 ± 0.66 logMAR (P = 0.043). The maximum keratometry (Kmax) value decreased from 63.6 ± 8.3D preoperatively to 59.6 ± 6.8D postoperatively (P = 0.043). Spherical equivalent improved from -11.2 ± 5.8D to -5.3 ± 3.1D (P = 0.043), and astigmatism reduced from -5.0 ± 3.4D to -3.3 ± 2.9D. Total corneal higher-order aberrations decreased from 5.6 ± 1.6D to 4.2 ± 1.6D postoperatively (P = 0.043).
Conclusions: Manual CAIRS is an effective treatment when a femtosecond laser is not available.
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