TM-free full utilization of S atoms: synthesis of thioethers from disulfides and quaternary ammonium salts†

Abstract

Disulfides are commonly used as alternatives of thiols; however, the full utilization of both S atoms of disulfides under TM-, oxidant/reductant-free conditions is still challenging. In this study, an efficient synthesis of thioethers from disulfides and quaternary ammonium salts under TM-, oxidant/reductant-free conditions has been developed. Both S atoms of disulfides can be transformed into thioether products, thus improving sulfur resource utilization. The method can be easily extended to the synthesis of valuable alkyl dithiocarbamates and can be readily scaled up to the gram scale, showing good practicality value.