Transition Metal Dichalcogenides in Biomedical Devices and Biosensors: A New Frontier for Precision Healthcare.

IF 5.4 2区 医学 Q2 MATERIALS SCIENCE, BIOMATERIALS
Eslam M Hamed, Sam F Y Li
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引用次数: 0

Abstract

Transition metal dichalcogenides (TMDs) have emerged as groundbreaking materials in the field of biomedical applications, particularly in the development of biosensors and medical devices. Their unique electronic and optical properties, combined with their tunability and biocompatibility, position TMDs as promising candidates for enhancing early disease detection and enabling personalized medicine. This perspective explores the multifaceted potential of TMDs, highlighting their applications in fluorescence and Raman-based biosensing, wearable and implantable devices, and smart therapeutic systems for targeted treatment. Additionally, we address critical challenges such as regulatory hurdles, long-term stability, and ethical considerations surrounding continuous health monitoring and data privacy. Looking to the future, we envision TMDs playing a vital role in the advancement of precision medicine, facilitating real-time health monitoring and individualized treatments. However, the successful integration of TMDs into clinical practice necessitates interdisciplinary collaboration among materials science, bioengineering, and clinical medicine. By fostering such collaboration, we can fully harness the capabilities of TMDs to revolutionize healthcare, making it more accessible, precise, and personalized for patients worldwide.

生物医学设备和生物传感器中的过渡金属二硫族化合物:精密医疗保健的新前沿。
过渡金属二硫族化合物(TMDs)已成为生物医学应用领域的突破性材料,特别是在生物传感器和医疗设备的开发方面。其独特的电子和光学特性,加上其可调性和生物相容性,使tmd成为加强早期疾病检测和实现个性化医疗的有希望的候选者。这一观点探讨了TMDs的多方面潜力,重点介绍了它们在荧光和基于拉曼的生物传感、可穿戴和植入式设备以及靶向治疗的智能治疗系统中的应用。此外,我们还解决了监管障碍、长期稳定性以及围绕持续健康监测和数据隐私的道德考虑等关键挑战。展望未来,我们预计tmd将在精准医疗的发展中发挥重要作用,促进实时健康监测和个性化治疗。然而,将tmd成功地整合到临床实践中需要材料科学、生物工程和临床医学之间的跨学科合作。通过促进这种合作,我们可以充分利用tmd的功能来彻底改变医疗保健,使其对全球患者来说更容易获得、更精确和更个性化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Biomaterials Science & Engineering
ACS Biomaterials Science & Engineering Materials Science-Biomaterials
CiteScore
10.30
自引率
3.40%
发文量
413
期刊介绍: ACS Biomaterials Science & Engineering is the leading journal in the field of biomaterials, serving as an international forum for publishing cutting-edge research and innovative ideas on a broad range of topics: Applications and Health – implantable tissues and devices, prosthesis, health risks, toxicology Bio-interactions and Bio-compatibility – material-biology interactions, chemical/morphological/structural communication, mechanobiology, signaling and biological responses, immuno-engineering, calcification, coatings, corrosion and degradation of biomaterials and devices, biophysical regulation of cell functions Characterization, Synthesis, and Modification – new biomaterials, bioinspired and biomimetic approaches to biomaterials, exploiting structural hierarchy and architectural control, combinatorial strategies for biomaterials discovery, genetic biomaterials design, synthetic biology, new composite systems, bionics, polymer synthesis Controlled Release and Delivery Systems – biomaterial-based drug and gene delivery, bio-responsive delivery of regulatory molecules, pharmaceutical engineering Healthcare Advances – clinical translation, regulatory issues, patient safety, emerging trends Imaging and Diagnostics – imaging agents and probes, theranostics, biosensors, monitoring Manufacturing and Technology – 3D printing, inks, organ-on-a-chip, bioreactor/perfusion systems, microdevices, BioMEMS, optics and electronics interfaces with biomaterials, systems integration Modeling and Informatics Tools – scaling methods to guide biomaterial design, predictive algorithms for structure-function, biomechanics, integrating bioinformatics with biomaterials discovery, metabolomics in the context of biomaterials Tissue Engineering and Regenerative Medicine – basic and applied studies, cell therapies, scaffolds, vascularization, bioartificial organs, transplantation and functionality, cellular agriculture
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