Line Claude, Sylvie Helfre, Nadège Corradini, Nathalie Gaspar, Pablo Berlanga, Laure Saumet, Perrine Marec-Bérard, Cyril Lervat, Mickael Ropars, Sophie Piperno-Neumann, Pascaline Boudou-Roquette, Gabriel Revon-Riviere, Anne Ducassou, Valentine Martin
{"title":"[Radiotherapy in Ewing sarcomas].","authors":"Line Claude, Sylvie Helfre, Nadège Corradini, Nathalie Gaspar, Pablo Berlanga, Laure Saumet, Perrine Marec-Bérard, Cyril Lervat, Mickael Ropars, Sophie Piperno-Neumann, Pascaline Boudou-Roquette, Gabriel Revon-Riviere, Anne Ducassou, Valentine Martin","doi":"10.1016/j.bulcan.2024.08.019","DOIUrl":null,"url":null,"abstract":"<p><p>Ewing sarcomas are the 2nd cause of malignant bone tumors in children and young adults. After induction chemotherapy, local treatment is essential and most often includes surgery of the primary tumor. Radiotherapy may be necessary as an exclusive local procedure when surgery is not possible, or in an adjuvant situation when the surgical procedure must be completed (incomplete resection or poor histological response in particular). Radiotherapy can also concern metastatic sites, particularly in cases of pulmonary metastases and/or in an oligo-metastatic situation. This article provides a review of current indications for radiotherapy, technical modalities of irradiation (delineation of volumes, recommended doses), and the results of recent studies.</p>","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin du cancer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.bulcan.2024.08.019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Ewing sarcomas are the 2nd cause of malignant bone tumors in children and young adults. After induction chemotherapy, local treatment is essential and most often includes surgery of the primary tumor. Radiotherapy may be necessary as an exclusive local procedure when surgery is not possible, or in an adjuvant situation when the surgical procedure must be completed (incomplete resection or poor histological response in particular). Radiotherapy can also concern metastatic sites, particularly in cases of pulmonary metastases and/or in an oligo-metastatic situation. This article provides a review of current indications for radiotherapy, technical modalities of irradiation (delineation of volumes, recommended doses), and the results of recent studies.