{"title":"[Research progress of acupuncture for modulating the inflammatory response in treatment of Parkinson's disease].","authors":"Si-Jia Hao, Shun Wang, Yan Bai, Pei-Zhu Lü, Cheng-Xiang Li, Ling-Yu Zhu, Hong-Xin Zhang","doi":"10.13702/j.1000-0607.20231039","DOIUrl":null,"url":null,"abstract":"<p><p>Parkinson's disease (PD) is a neurodegenerative disease commonly seen in middle-aged and elderly people. Acupuncture can effectively reduce the symptoms of PD and improve the life quality of patients. In this paper, we reviewed the relevant literature on acupuncture modulation of PD inflammation in recent years from the perspective of neuroinflammation. The results showed that the mechanism of acupuncture for inflammatory responses in treatment of PD is closely related to inhibiting the glial cell activation, regulating the peripheral immune cells, suppressing the release of inflammatory factors, inducing anti-inflammatory factor expression, modulating the expression of inflammatory signaling pathways, and attenuating the intestinal inflammation. It may be effective for alleviating neuroinflammation, reducing neuronal damage, and delaying the progression of PD. This paper provides the evidences and ideas for the deepening research of the mechanism of PD treated with acupuncture and moxibustion in the future.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 3","pages":"334-340"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"针刺研究","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13702/j.1000-0607.20231039","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Parkinson's disease (PD) is a neurodegenerative disease commonly seen in middle-aged and elderly people. Acupuncture can effectively reduce the symptoms of PD and improve the life quality of patients. In this paper, we reviewed the relevant literature on acupuncture modulation of PD inflammation in recent years from the perspective of neuroinflammation. The results showed that the mechanism of acupuncture for inflammatory responses in treatment of PD is closely related to inhibiting the glial cell activation, regulating the peripheral immune cells, suppressing the release of inflammatory factors, inducing anti-inflammatory factor expression, modulating the expression of inflammatory signaling pathways, and attenuating the intestinal inflammation. It may be effective for alleviating neuroinflammation, reducing neuronal damage, and delaying the progression of PD. This paper provides the evidences and ideas for the deepening research of the mechanism of PD treated with acupuncture and moxibustion in the future.
期刊介绍：
Acupuncture Research was founded in 1976. It is an acupuncture academic journal supervised by the State Administration of Traditional Chinese Medicine, co-sponsored by the Institute of Acupuncture of the China Academy of Chinese Medical Sciences and the Chinese Acupuncture Association. This journal is characterized by "basic experimental research as the main focus, taking into account clinical research and reporting". It is the only journal in my country that focuses on reporting the mechanism of action of acupuncture.
The journal has been changed to a monthly journal since 2018, published on the 25th of each month, and printed in full color. The manuscript acceptance rate is about 10%, and provincial and above funded projects account for about 80% of the total published papers, reflecting the latest scientific research results in the acupuncture field and has a high academic level. Main columns: mechanism discussion, clinical research, acupuncture anesthesia, meridians and acupoints, theoretical discussion, ideas and methods, literature research, etc.
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