Stereotactic radiotherapy for spinal and non-spinal bone metastases: a patterns-of-care analysis in German-speaking countries as part of a project of the interdisciplinary Radiosurgery and Stereotactic Radiotherapy Working Group of the DEGRO/DGMP.

IF 2.7 3区医学 Q3 ONCOLOGY

Strahlentherapie und Onkologie Pub Date : 2025-03-18 DOI:10.1007/s00066-025-02387-y

F Nägler, N Gleim, I Seiler, A Rühle, K Hering, C Seidel, E Gkika, D Krug, O Blanck, C Moustakis, T B Brunner, A Wittig-Sauerwein, N H Nicolay

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引用次数: 0

Abstract

Background and purpose: Bone metastases constitute a common indication for both conventional radiotherapy (RT) and stereotactic body radiotherapy (SBRT). Although in recent years guidelines have been proposed for SBRT of spinal and non-spinal metastases, little is known about the use of bone SBRT and the actual patterns of care in German-speaking countries.

Material and methods: We performed an online survey among radiation oncologists (ROs) registered with the interdisciplinary Radiosurgery and Stereotactic Radiotherapy Working Group of the German Society of Radiation Oncology (DEGRO) and the German Society for Medical Physics (DGMP) to collect valuable and robust cross-sectional data on patterns of care for bone SBRT in German-speaking countries.

Results: Of the registered ROs, 35.5% (75/211) completed the online survey. ROs working in high-volume centers irradiating more than 100 patients with bone metastases annually represented the largest group, with 58.7%. Ablative SBRT was mostly performed for bone oligometastases (78.7%). For symptom-directed palliative radiotherapy, the majority of responding physicians (84.3%) still mostly recommend moderately hypofractionated treatment. Nevertheless, 60.9% of participating ROs stated using bone SBRT at least occasionally, also for palliative purposes such as pain control. Our survey also revealed a certain reluctance for the concomitant use of systemic therapies with bone SBRT and heterogeneity regarding target volume definition and dosing for bone SBRT.

Conclusion: Our survey demonstrates that bone SBRT for spinal and non-spinal metastases for oligometastatic disease (OMD) is broadly available in clinical routine care in German-speaking countries. A large heterogeneity regarding indications, dose, and fractionation concepts remains, requiring further efforts for standardization of bone SBRT.

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脊柱和非脊柱骨转移的立体定向放疗：德语国家的护理模式分析，作为DEGRO/DGMP跨学科放射外科和立体定向放疗工作组项目的一部分。

背景与目的：骨转移是常规放射治疗（RT）和立体定向放射治疗（SBRT）的常见适应症。尽管近年来已经提出了脊柱和非脊柱转移的SBRT指南，但对于骨SBRT的使用和德语国家的实际护理模式知之甚少。材料和方法：我们在德国放射肿瘤学学会（DEGRO）和德国医学物理学会（DGMP）的跨学科放射外科和立体定向放疗工作组注册的放射肿瘤学家（ROs）中进行了一项在线调查，以收集有关德语国家骨SBRT护理模式的有价值和可靠的横断面数据。结果：在已登记的ro中，35.5%（75/211）完成了在线调查。在每年放疗超过100例骨转移患者的大容量中心工作的ROs占58.7%，是最大的群体。消融性SBRT主要用于骨少转移（78.7%）。对于以症状为导向的姑息性放疗，大多数受访医师（84.3%）仍然大多推荐中度低分割治疗。然而，60.9%的参与者表示至少偶尔使用骨SBRT，也用于缓解疼痛等目的。我们的调查还显示，对于骨SBRT同时使用全身治疗存在一定的不情愿，并且骨SBRT的靶体积定义和剂量存在异质性。结论：我们的调查表明，骨SBRT治疗脊柱和非脊柱转移性少转移性疾病（OMD）在德语国家的临床常规护理中广泛可用。关于适应症、剂量和分离概念仍然存在很大的异质性，需要进一步努力实现骨SBRT的标准化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Strahlentherapie und Onkologie 医学-核医学

CiteScore

5.70

自引率

12.90%

发文量

141

审稿时长

3-8 weeks

期刊介绍： Strahlentherapie und Onkologie, published monthly, is a scientific journal that covers all aspects of oncology with focus on radiooncology, radiation biology and radiation physics. The articles are not only of interest to radiooncologists but to all physicians interested in oncology, to radiation biologists and radiation physicists. The journal publishes original articles, review articles and case studies that are peer-reviewed. It includes scientific short communications as well as a literature review with annotated articles that inform the reader on new developments in the various disciplines concerned and hence allow for a sound overview on the latest results in radiooncology research. Founded in 1912, Strahlentherapie und Onkologie is the oldest oncological journal in the world. Today, contributions are published in English and German. All articles have English summaries and legends. The journal is the official publication of several scientific radiooncological societies and publishes the relevant communications of these societies.