Computed tomography manifestations and pathological features of intra-abdominal desmoplastic small round cell tumor.

IF 1.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Pakistan Journal of Medical Sciences Pub Date : 2025-03-01 DOI:10.12669/pjms.41.3.10154

Ashan Pan, Xunze Shen, Qiande Qiu

{"title":"Computed tomography manifestations and pathological features of intra-abdominal desmoplastic small round cell tumor.","authors":"Ashan Pan, Xunze Shen, Qiande Qiu","doi":"10.12669/pjms.41.3.10154","DOIUrl":null,"url":null,"abstract":"Objective: To explore the computed tomography (CT) manifestations and pathological features of intra-abdominal desmoplastic small round cell tumor (DSRCT).Methods: Retrospective analysis was conducted on the CT manifestations and pathological features of 11 patients with intra-abdominal DSRCT in Yueqing People's Hospital, Shaoxing People's Hospital and Wenzhou People's Hospital from January 2010 to June 2022.Results: Among 11 patients, four cases were with solitary tumor and seven cases were with multiple tumors. There were five cases with elliptical shape, smooth edges and clear boundary and six cases with irregular shape and unclear boundary. The CT plain scan showed the uneven density in tumor. There were six cases with necrosis and cystic transformation in central tumor, and five cases with small patchy or strip-shaped calcification within the tumor. The enhanced CT scan showed uneven enhancement. There were seven cases of mild enhancement and four cases of moderate enhancement. Five cases showed strip or grid-like enhancement within tumor, and five cases showed increased and thickened vascular shadows around the tumor. The immunohistochemistry showed nine cases were positive for AE1/AE3, CK, Vim and Desmin, eight cases were positive for EMA, seven cases were positive for NSE, and three cases were positive for CGA, SYN, CD56 and CD99.Conclusion: In CT manifestations, the intra-abdominal DSRCT present the solitary or multiple tumors, with uneven density. There are often cystic changes and small patchy calcification within the tumor, with mild to moderate uneven enhancement.","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 3","pages":"753-757"},"PeriodicalIF":1.2000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11911772/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan Journal of Medical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12669/pjms.41.3.10154","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To explore the computed tomography (CT) manifestations and pathological features of intra-abdominal desmoplastic small round cell tumor (DSRCT).

Methods: Retrospective analysis was conducted on the CT manifestations and pathological features of 11 patients with intra-abdominal DSRCT in Yueqing People's Hospital, Shaoxing People's Hospital and Wenzhou People's Hospital from January 2010 to June 2022.

Results: Among 11 patients, four cases were with solitary tumor and seven cases were with multiple tumors. There were five cases with elliptical shape, smooth edges and clear boundary and six cases with irregular shape and unclear boundary. The CT plain scan showed the uneven density in tumor. There were six cases with necrosis and cystic transformation in central tumor, and five cases with small patchy or strip-shaped calcification within the tumor. The enhanced CT scan showed uneven enhancement. There were seven cases of mild enhancement and four cases of moderate enhancement. Five cases showed strip or grid-like enhancement within tumor, and five cases showed increased and thickened vascular shadows around the tumor. The immunohistochemistry showed nine cases were positive for AE1/AE3, CK, Vim and Desmin, eight cases were positive for EMA, seven cases were positive for NSE, and three cases were positive for CGA, SYN, CD56 and CD99.

Conclusion: In CT manifestations, the intra-abdominal DSRCT present the solitary or multiple tumors, with uneven density. There are often cystic changes and small patchy calcification within the tumor, with mild to moderate uneven enhancement.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Pakistan Journal of Medical Sciences 医学-医学：内科

CiteScore

4.10

自引率

9.10%

发文量

363

审稿时长

3-6 weeks

期刊介绍： It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad. Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.