Heart rate variability during exercise can quantify cardiorespiratory deconditioning in 55- to 65-year-old men and women exposed to head-down bed rest.

IF 3.3 3区 医学 Q1 PHYSIOLOGY
Jeremy Rabineau, Eric T Hedge, Roxanne Fournier, Carmelo J Mastrandrea, Richard L Hughson
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引用次数: 0

Abstract

The heart rate variability (HRV) features HRV0.75 and HRV0.5, obtained by detrended fluctuation analysis during incremental cycle ergometer tests, have been shown to correlate with indices of cardiorespiratory fitness. Here, we evaluate the ability of these features to track individual changes in cardiorespiratory fitness induced by head-down bed rest (HDBR) among late middle-aged adults. Twenty-two healthy participants (55-65 years old, 11 women) were exposed to 14-day HDBR. Eleven participants were assigned to a group performing daily aerobic and resistive exercises during HDBR, while the others were assigned to a control group with no countermeasure intervention. We measured gas exchange and electrocardiography during incremental cycle ergometer tests pre- and post-HDBR. The countermeasure preserved oxygen uptake (V̇O2) at the two ventilatory thresholds (VT1 and VT2), HRV0.75 and HRV0.5. However, these four features decreased in the control group after HDBR. A large and proportional bias was evidenced between V̇O2 at VT1 and HRV0.75, which was less the case for V̇O2 at VT2 versus HRV0.5. However, the intra-individual changes in the control group were correlated (rrm = 0.66 for VT1 vs. HRV0.75 and rrm = 0.82 for V̇O2 at VT2 versus HRV0.5, both p < 0.001). Overall, this study indicated that HRV0.75 and HRV0.5 can be used to longitudinally monitor changes in cardiorespiratory fitness in late middle-aged adults with physical deconditioning. Future research can apply these methods to other study populations.

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来源期刊
CiteScore
6.00
自引率
9.10%
发文量
296
审稿时长
2-4 weeks
期刊介绍: The Journal of Applied Physiology publishes the highest quality original research and reviews that examine novel adaptive and integrative physiological mechanisms in humans and animals that advance the field. The journal encourages the submission of manuscripts that examine the acute and adaptive responses of various organs, tissues, cells and/or molecular pathways to environmental, physiological and/or pathophysiological stressors. As an applied physiology journal, topics of interest are not limited to a particular organ system. The journal, therefore, considers a wide array of integrative and translational research topics examining the mechanisms involved in disease processes and mitigation strategies, as well as the promotion of health and well-being throughout the lifespan. Priority is given to manuscripts that provide mechanistic insight deemed to exert an impact on the field.
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