Effectiveness of Digital Health Interventions in Promoting the Pre-Exposure Prophylaxis (PrEP) Care Continuum among Men who Have Sex With Men (MSM): A Systematic Review of Randomized Controlled Trials.

IF 3.7 2区医学 Q2 INFECTIOUS DISEASES

Current HIV/AIDS Reports Pub Date : 2025-03-18 DOI:10.1007/s11904-025-00733-4

Jun Du, Guifang Jin, Hongbo Zhang, Operario Don, Haiyan Shi, Sainan Wang, Jun Wang, Yehuan Sun, Zhihua Zhang

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引用次数: 0

Abstract

Purpose of review: Digital health interventions have demonstrated great potential to advance HIV prevention and care. However, their effectiveness in improving the pre-exposure prophylaxis (PrEP) care continuum has not yet been validated. This systematic review aimed to evaluate the effectiveness of digital health interventions in enhancing the PrEP care continuum among men who have sex with men (MSM) populations.

Recent finding: Following PRISMA guidelines, a comprehensive search was conducted across four databases-PubMed, Web of Science, Embase, and Cochrane Library-to identify randomized controlled trials (RCTs) published before July 2, 2024. Out of the 3,539 records initially identified, 12 RCTs met the inclusion criteria. The majority of the studies were conducted in the United States (10/12, 83.3%), with the remaining 2 studies conducted in China. Participant ages ranged from 18 to 65 years. The studies employed various digital health tools, including mobile apps, text message, and social media platforms. While digital health interventions were found to be feasible and acceptable, only a few studies demonstrated statistically significant increases in PrEP utilization and adherence. Digital health interventions have demonstrated potential to enhance the PrEP care continuum in MSM populations. Future research should focus on large-scale, multicenter trials that combine digital tools with personalized, culturally sensitive strategies to improve PrEP uptake and adherence. Integrating big data, artificial intelligence (AI), and non-digital approaches like community outreach and psychosocial support could further strengthen the effectiveness of these interventions.

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数字健康干预在促进男男性行为者暴露前预防（PrEP）护理连续性中的有效性：随机对照试验的系统评价

审查目的：数字卫生干预措施已显示出促进艾滋病毒预防和护理的巨大潜力。然而，它们在改善暴露前预防（PrEP）连续护理方面的有效性尚未得到证实。本系统综述旨在评估数字健康干预措施在加强男男性行为人群（MSM）中PrEP护理连续性方面的有效性。最新发现：遵循PRISMA指南，在pubmed， Web of Science， Embase和Cochrane library四个数据库中进行了全面搜索，以确定在2024年7月2日之前发表的随机对照试验（rct）。在最初确定的3539条记录中，12项rct符合纳入标准。大多数研究在美国进行（10/12,83.3%），其余2项研究在中国进行。参与者年龄从18岁到65岁不等。这些研究使用了各种数字健康工具，包括移动应用程序、短信和社交媒体平台。虽然发现数字卫生干预措施是可行和可接受的，但只有少数研究表明，PrEP的利用和依从性在统计上有显著增加。数字卫生干预措施已证明有潜力加强男男性行为者群体的PrEP护理连续性。未来的研究应侧重于大规模、多中心的试验，将数字工具与个性化、文化敏感的策略相结合，以提高PrEP的吸收和依从性。整合大数据、人工智能（AI）以及社区外展和社会心理支持等非数字方法，可以进一步加强这些干预措施的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current HIV/AIDS Reports INFECTIOUS DISEASES-

CiteScore

8.10

自引率

2.20%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of HIV/AIDS. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as antiretroviral therapies, behavioral aspects of management, and metabolic complications and comorbidity. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.