Advancing analytical chemistry with carbon quantum dots: a comprehensive review

IF 2.7 3区化学 Q2 CHEMISTRY, ANALYTICAL

Analytical Methods Pub Date : 2025-03-05 DOI:10.1039/D4AY02237H

Ilyos Eliboev, Alisher Ishankulov, Elyor Berdimurodov, Komiljan Chulpanov, Maksud Nazarov, Berdiyev Jamshid, Bekzod Toshpulotov, Rano Tukhtaeva, Muslum Demir, Kamila Rashidova, Fazliddin Jalilov and Khudaybergan Polvonov

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Abstract

Carbon Quantum Dots (CQDs) have gained significant attention as versatile nanomaterials in analytical chemistry due to their strong fluorescence, high sensitivity, and biocompatibility features. This review explores the synthesis, functionalization, and broad applications of CQDs in various analytical domains, including bioimaging, diagnostics, and environmental monitoring. CQDs' unique properties, such as tunable emission and ease of surface modification, enhance their performance in fluorescence and electrochemical sensing. CQDs present emerging applications in single-cell analysis, point-of-care diagnostics, and food safety. Technological advancements in green synthesis and hybrid nanomaterial integration are paving the way for more sustainable, efficient, and scalable analytical tools. However, challenges related to reproducibility, stability, and large-scale production persist, highlighting the need for continued research. The present review provides a comprehensive overview of CQDs' impact, emphasizing their potential to transform analytical chemistry through innovative applications and future breakthroughs.

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碳量子点（CQDs）由于其强荧光、高灵敏度和生物相容性等特性，在分析化学领域得到了广泛的关注。本文综述了CQDs的合成、功能化及其在生物成像、诊断和环境监测等分析领域的广泛应用。CQDs的独特性质，如可调谐发射和易于表面修饰，增强了它们在荧光和电化学传感方面的性能。CQDs在单细胞分析、即时诊断和食品安全方面呈现出新的应用。绿色合成和混合纳米材料集成的技术进步为更可持续、高效和可扩展的分析工具铺平了道路。然而，与可重复性、稳定性和大规模生产相关的挑战仍然存在，突出了继续研究的必要性。本文综述了CQDs的影响，强调了它们通过创新应用和未来突破改变分析化学的潜力。

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