Recent Vaccines against Emerging and Tropical Infectious Diseases.

Discoveries (Craiova, Romania) Pub Date : 2024-06-30 eCollection Date: 2024-04-01 DOI:10.15190/d.2024.6
Ismail Mazhar, Mir Muhammad Rai, Abdullah Ahmad, Natasha Nadeem, Aamir Shahid Javed, Hassan Mumtaz
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Abstract

Emerging diseases, re-emerging diseases and tropical diseases are a slowly progressing problem globally. This may in part be the result of shifting population, growing poverty, inadequate distribution of resources, or even complacency against personal hygiene. As a result of the low income and low standards of health in developing countries, they provide the perfect breeding grounds for the pathogens and parasites that are the root cause of Neglected Tropical diseases (NTDs). In the case of emerging diseases, most are of zoonotic origin and the recent COVID-19 pandemic is a key example. However, it is not just new diseases but re-emerging diseases such as Influenza that highlight the relentless nature of these infections. Vaccines represent the ultimate safety net against these diseases by bolstering immune systems and lowering subsequent mortality and morbidity of these conditions. In fact, against diseases with high mortalities such as AIDS, Hepatitis, and Malaria, vaccine development has markedly reduced mortality and prolonged life expectancy of those afflicted with these conditions. However, this research highlights the importance of enhancing vaccine efficacy and response. The review further underscores the necessity of research, the timing of vaccine administration, effective resource management by governments, and the perception of the population. Therefore, the review offers valuable insights for the medical community and the pharmaceutical industry in improving research and management to maximize the potential of vaccines.

Abstract Image

预防新发和热带传染病的最新疫苗。
新发疾病、再发疾病和热带疾病是一个缓慢发展的全球性问题。部分原因可能是人口流动、贫困加剧、资源分配不足,甚至是对个人卫生的自满。由于发展中国家的低收入和低卫生标准,它们为病原体和寄生虫提供了完美的滋生地,而这些病原体和寄生虫是被忽视的热带病的根本原因。就新出现的疾病而言,大多数是人畜共患疾病,最近的COVID-19大流行就是一个重要例子。然而,不仅是新出现的疾病,流感等重新出现的疾病也突显了这些感染的无情性质。疫苗通过增强免疫系统和降低这些疾病的死亡率和发病率,代表了对抗这些疾病的最终安全网。事实上,针对艾滋病、肝炎和疟疾等死亡率高的疾病,疫苗的开发显著降低了这些疾病患者的死亡率,延长了他们的预期寿命。然而,这项研究强调了加强疫苗效力和反应的重要性。审查进一步强调了研究的必要性、接种疫苗的时机、政府有效的资源管理以及民众的看法。因此,该综述为医学界和制药业改善研究和管理以最大限度地发挥疫苗的潜力提供了宝贵的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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