Epidemiology and occupational risk factors of male infertility based on 3,025 patients in Eastern Morocco during 2021-2023: a cohort study.

IF 2 Q2 OBSTETRICS & GYNECOLOGY
Obstetrics and Gynecology Science Pub Date : 2025-05-01 Epub Date: 2025-03-17 DOI:10.5468/ogs.24297
Chaymae Rochdi, Meriem Ouadrhiri, Ibtissam Bellajdel, Hafsa Taheri, Hanane Saadi, Ahmed Mimouni, Mohammed Choukri
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引用次数: 0

Abstract

Objective: The objective of our study was to characterize the sperm parameters of men consulting for infertility in our fertility center.

Methods: The study included 3,025 patients investigated from September 2021 to July 2023. Demographic data, infertility risk factors, and the primary or secondary nature of infertility were recorded for each patient. The sperm parameters were analyzed according to World Health Organization (WHO) criteria (2021).

Results: The average age of the patients was 40 years. The average duration of infertility was 5.5 years. Primary infertility was noted in 2,736 patients (88.97%). The most common risk factors for infertility were occupational exposure, followed by varicocele. Lifestyle factors associated with male infertility included smoking (24.29%), alcohol consumption (12.49%), and high temperature exposure (30.08%). Spermogram abnormalities were observed in 78.71% of cases. Spermocytogram abnormalities were found in 63.1% of cases. Sperm count, morphology, total motility, and vitality below WHO (2021) reference values were found in 25.60%, 34.13%, 32.29%, and 62.46% of the analyzed samples, respectively. Seminal fluid analysis revealed oligozoospermia in 29.07% of cases, asthenozoospermia in 24.68%, and azoospermia in 17.56%. Oligo-astheno-necrospermia was the most frequently observed combined abnormality (10.0%).

Conclusion: This study showed a high rate of abnormal semen quality in male partners of infertile couples. Male infertility is often multifactorial and results in quantitative and/or qualitative sperm abnormalities.

2021-2023年摩洛哥东部3025例男性不育症的流行病学和职业危险因素:一项队列研究
目的:本研究的目的是了解在生育中心就诊的男性不育患者的精子参数。方法:该研究纳入了2021年9月至2023年7月期间调查的3025例患者。记录每位患者的人口统计数据、不孕症危险因素和不孕症的原发或继发性质。精子参数根据世界卫生组织(WHO)标准(2021年)进行分析。结果:患者平均年龄40岁。不孕的平均持续时间为5.5年。原发性不孕症2736例(88.97%)。不孕最常见的危险因素是职业性暴露,其次是精索静脉曲张。与男性不育相关的生活方式因素包括吸烟(24.29%)、饮酒(12.49%)和高温暴露(30.08%)。78.71%的病例精子图异常。63.1%的病例精细胞图异常。精子数量、形态、总活动力和活力低于WHO(2021)参考值的比例分别为29.07%、34.13%、32.29%和62.46%。精液分析显示少精子症29.07%,弱精子症24.68%,无精子症17.56%。少精弱精坏死是最常见的合并异常(10.0%)。结论:本研究显示不育夫妇男性精液质量异常发生率高。男性不育通常是多因素的,导致精子数量和/或质量异常。
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来源期刊
Obstetrics and Gynecology Science
Obstetrics and Gynecology Science Medicine-Obstetrics and Gynecology
CiteScore
3.80
自引率
15.80%
发文量
58
审稿时长
16 weeks
期刊介绍: Obstetrics & Gynecology Science (NLM title: Obstet Gynecol Sci) is an international peer-review journal that published basic, translational, clinical research, and clinical practice guideline to promote women’s health and prevent obstetric and gynecologic disorders. The journal has an international editorial board and is published in English on the 15th day of every other month. Submitted manuscripts should not contain previously published material and should not be under consideration for publication elsewhere. The journal has been publishing articles since 1958. The aim of the journal is to publish original articles, reviews, case reports, short communications, letters to the editor, and video articles that have the potential to change the practices in women''s health care. The journal’s main focus is the diagnosis, treatment, prediction, and prevention of obstetric and gynecologic disorders. Because the life expectancy of Korean and Asian women is increasing, the journal''s editors are particularly interested in the health of elderly women in these population groups. The journal also publishes articles about reproductive biology, stem cell research, and artificial intelligence research for women; additionally, it provides insights into the physiology and mechanisms of obstetric and gynecologic diseases.
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